CAS 58562-46-2
:2-(2-Nitrophenoxy)acetamide
Description:
2-(2-Nitrophenoxy)acetamide, with the CAS number 58562-46-2, is an organic compound characterized by its amide functional group and a nitrophenoxy substituent. This compound typically appears as a solid at room temperature and is soluble in organic solvents, reflecting its polar nature due to the presence of both the nitro and amide groups. The nitrophenoxy moiety contributes to its potential as a synthetic intermediate in organic chemistry, particularly in the development of pharmaceuticals and agrochemicals. The presence of the nitro group can also impart unique electronic properties, making it useful in various chemical reactions, including nucleophilic substitutions and coupling reactions. Additionally, the compound may exhibit biological activity, which could be of interest in medicinal chemistry. Safety data should be consulted for handling and storage, as compounds with nitro groups can sometimes be hazardous. Overall, 2-(2-Nitrophenoxy)acetamide serves as an important building block in chemical synthesis and research applications.
Formula:C8H8N2O4
InChI:InChI=1S/C8H8N2O4/c9-8(11)5-14-7-4-2-1-3-6(7)10(12)13/h1-4H,5H2,(H2,9,11)
InChI key:InChIKey=DVCVYHFEWYAJCP-UHFFFAOYSA-N
SMILES:O(CC(N)=O)C1=C(N(=O)=O)C=CC=C1
Synonyms:- 2-(2-Nitrophenoxy)acetamide
- Acetamide, 2-(2-nitrophenoxy)-
- Acetamide, 2-(o-nitrophenoxy)-
- 2-(Carbamoylmethoxy)nitrobenzene
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Found 2 products.
2-(2-Nitrophenoxy)acetamide
CAS:2-(2-Nitrophenoxy)acetamide (NPA) is a nitro-substituted nitroaromatic compound that has been shown to inhibit the activity of the P-glycoprotein efflux pump. This inhibitory effect may be due to its ability to bind to the ATP binding site on the P-glycoprotein, which prevents ATP hydrolysis and energy transfer. 2-(2-Nitrophenoxy)acetamide also inhibits cancer cells, as it utilizes adenosine triphosphate (ATP) as an energy source. NPA also displays an inhibitory effect on other cellular functions, including transport of substances across membranes and inhibition of DNA synthesis in human cells.Formula:C8H8N2O4Purity:Min. 95%Molecular weight:196.16 g/mol
