CymitQuimica logo

CAS 58581-89-8

:

Azelastine

Description:
Azelastine is a pharmaceutical compound primarily used as an antihistamine for the treatment of allergic conditions, such as allergic rhinitis and conjunctivitis. It belongs to the class of drugs known as H1 receptor antagonists, which work by blocking the action of histamine, a substance in the body that causes allergic symptoms. Azelastine is characterized by its relatively high lipophilicity, which enhances its ability to penetrate tissues, including the nasal mucosa and ocular tissues. The compound is typically administered as a nasal spray or eye drops, allowing for localized action with minimal systemic absorption. Azelastine exhibits a rapid onset of action, providing relief from symptoms such as sneezing, itching, and nasal congestion. Additionally, it has a long duration of action, which contributes to its effectiveness in managing allergic responses. The chemical structure of azelastine includes a phthalazinone moiety, which is essential for its pharmacological activity. Overall, azelastine is recognized for its efficacy and safety profile in treating allergic reactions.
Formula:C22H24ClN3O
InChI:InChI=1S/C22H24ClN3O/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16/h2-3,6-11,18H,4-5,12-15H2,1H3
InChI key:InChIKey=MBUVEWMHONZEQD-UHFFFAOYSA-N
SMILES:C(C=1C=2C(C(=O)N(N1)C3CCCN(C)CC3)=CC=CC2)C4=CC=C(Cl)C=C4
Synonyms:
  • 1(2H)-Phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-
  • 4-(4-Chlorobenzyl)-2-(1-methylazepan-4-yl)-1-oxo-1,4-dihydrophthalazin-2-ium
  • 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone
  • 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-4H-phthalazin-2-ium-1-one
  • phthalazinium, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1,4-dihydro-1-oxo-
  • Azelastine
  • (±)-Azelastine
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 5 products.