CAS 58584-83-1

2,6-Dichloro-3-pyridinecarbonyl chloride

Description:

2,6-Dichloro-3-pyridinecarbonyl chloride, with the CAS number 58584-83-1, is a chemical compound characterized by its pyridine ring structure substituted with two chlorine atoms and a carbonyl chloride functional group. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its physical state at room temperature. It is known for its reactivity, particularly as an acyl chloride, which makes it useful in organic synthesis for introducing acyl groups into various substrates. The presence of chlorine atoms enhances its electrophilic character, facilitating nucleophilic attack by amines, alcohols, or other nucleophiles. Additionally, 2,6-Dichloro-3-pyridinecarbonyl chloride is sensitive to moisture and should be handled with care, as it can hydrolyze to form hydrochloric acid and the corresponding pyridinecarboxylic acid. Its applications may include the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals, making it a valuable intermediate in chemical manufacturing. Proper safety precautions should be taken due to its corrosive nature and potential health hazards.

Formula: C₆H₂Cl₃NO

InChI: InChI=1S/C6H2Cl3NO/c7-4-2-1-3(6(9)11)5(8)10-4/h1-2H

InChI key: InChIKey=JHMHYTKDALCQSZ-UHFFFAOYSA-N

SMILES: C(Cl)(=O)C1=C(Cl)N=C(Cl)C=C1

Synonyms:

• 2,6-Dichloronicotinyl chloride
• 2,6-Dichloronicotinoyl chloride
• 3-Pyridinecarbonyl chloride, 2,6-dichloro-
• 2,6-Dichloropyridine-3-carbonyl chloride
• 2,6-Dichloro-3-pyridinecarbonyl chloride
• EOS-62046
• 2,6-Dichloronicotinoyl chloride ISO 9001：2015 REACH
• 2,6-Dichloropyridine-3-carbonyl chloride 96%
• 2,6-Dichloropyridine-3-carboxylic chloride

2,6-Dichloropyridine-3-carbonyl chloride

CAS: 58584-83-1

Formula: C₆H₂Cl₃NO

Purity: 95%

Color and Shape: Liquid

Molecular weight: 210.4452

Ref: IN-DA003G3T

2,6-Dichloronicotinoyl chloride

CAS: 58584-83-1

2,6-Dichloronicotinoyl chloride

Purity: 95%

Molecular weight: 210.45g/mol

Ref: 54-OR1073679

2,6-Dichloronicotinyl Chloride

Controlled Product

CAS: 58584-83-1

Applications 2,6-Dichloronicotinyl Chloride is a reactant used in the preparation of semisynthetic derivatives of andrographolide and inhibitors of hepatitis C (HCV) NS5B polymerase.
References Uttekar, M. et al.: Eur. J. Med. Chem., 56, 368 (2012); Reddy, T. et al.: Bioorg. Med. Chem. Lett., 13, 3341 (2003)

Formula: C₆H₂Cl₃NO

Color and Shape: Neat

Molecular weight: 210.45

Ref: TR-D435520