CAS 586-75-4

4-Bromobenzoyl chloride

Description:

4-Bromobenzoyl chloride, with the CAS number 586-75-4, is an aromatic acyl chloride characterized by the presence of a bromine atom at the para position relative to the carbonyl group in the benzoyl structure. This compound is typically a colorless to pale yellow liquid with a pungent odor, indicative of its reactivity. It is soluble in organic solvents such as dichloromethane and ether but reacts with water, releasing hydrochloric acid and forming 4-bromobenzoic acid. The presence of the acyl chloride functional group makes it a potent electrophile, allowing it to participate in various chemical reactions, including acylation and the formation of amides and esters. Due to its reactivity, 4-bromobenzoyl chloride must be handled with care, as it can cause severe irritation to the skin, eyes, and respiratory system. It is commonly used in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals, where the introduction of the bromine atom can enhance biological activity or modify chemical properties.

Formula: C₇H₄BrClO

InChI: InChI=1S/C7H4BrClO/c8-6-3-1-5(2-4-6)7(9)10/h1-4H

InChI key: InChIKey=DENKGPBHLYFNGK-UHFFFAOYSA-N

SMILES: C(Cl)(=O)C1=CC=C(Br)C=C1

Synonyms:

• 4-Brombenzoylchlorid
• 4-Bromo-1-benzenecarbonyl chloride
• 4-Brorobenzoylchloride
• Benzoyl chloride, 4-bromo-
• Benzoyl chloride, p-bromo-
• Chlorure de 4-bromobenzoyle
• Cloruro De 4-Bromobenzoilo
• Nsc 7091
• p-Bromobenzoyl chloride
• 4-Bromobenzoyl chloride

4-Bromobenzoyl Chloride

CAS: 586-75-4

Formula: C₇H₄BrClO

Purity: >98.0%(GC)(T)

Color and Shape: White to Orange to Green powder to lump

Molecular weight: 219.46

Ref: 3B-B0558

4-Bromobenzoyl chloride, 98+%

CAS: 586-75-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₄BrClO

Purity: 98+%

Color and Shape: White to cream to brown, Crystals or powder or crystalline powder or lumps or fused solid

Molecular weight: 219.46

Ref: 02-L03794

4-Bromobenzoyl chloride

CAS: 586-75-4

4-Bromobenzoyl chloride

Formula: C₇H₄BrClO

Purity: 98%

Color and Shape: white fused solid

Molecular weight: 219.46306g/mol

Ref: 54-OR52101

4-Bromobenzoyl chloride

CAS: 586-75-4

Formula: C₇H₄BrClO

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 219.46

Ref: 10-F013058

4-Bromobenzoyl chloride

CAS: 586-75-4

4-Bromobenzoyl chloride is a molecule consisting of a bromine atom and 4 carbons, with a hydroxyl group on the second carbon. It is an acylation reaction product that can be formed from hydrochloric acid and benzoyl chloride, or from primary cells in water vapor. The diphenyl ether and aryl halide react to form 4-bromobenzoyl chloride in the presence of boron nitride. This reaction mechanism may occur in vivo when the mcl-1 protein is inhibited. 4-Bromobenzoyl chloride has been shown to be active against cancer cells in vitro, but not against normal cells, suggesting that it may be used as an anticancer agent. Crystallography studies have shown that 4-bromobenzoyl chloride has intramolecular hydrogen bonds which stabilize its structure.

Formula: C₇H₄BrClO

Purity: Min. 95%

Molecular weight: 219.46 g/mol

Ref: 3D-FB10832