CAS 5863-35-4

Pyrrolidine, 1-[2-[4-[1-(4-methoxyphenyl)-2-nitro-2-phenylethenyl]phenoxy]ethyl]-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

Description:

Pyrrolidine, 1-[2-[4-[1-(4-methoxyphenyl)-2-nitro-2-phenylethenyl]phenoxy]ethyl]-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1), with CAS number 5863-35-4, is a complex organic compound characterized by its multi-functional structure. It features a pyrrolidine ring, which is a five-membered nitrogen-containing heterocycle, contributing to its potential biological activity. The presence of a phenoxy group and a methoxy-substituted phenyl moiety suggests that the compound may exhibit significant lipophilicity, potentially influencing its solubility and interaction with biological membranes. The nitro group indicates possible reactivity and the potential for biological activity, while the tricarboxylate component may impart acidity and chelating properties. This compound may be of interest in medicinal chemistry due to its structural complexity and the potential for diverse pharmacological effects. However, specific properties such as melting point, boiling point, and solubility would require empirical data for precise characterization. Overall, the intricate structure of this compound suggests a variety of potential applications in research and development.

Formula: C₂₇H₂₈N₂O₄·C₆H₈O₇

InChI: InChI=1S/C27H28N2O4.C6H8O7/c1-32-24-13-9-21(10-14-24)26(27(29(30)31)23-7-3-2-4-8-23)22-11-15-25(16-12-22)33-20-19-28-17-5-6-18-28;7-3(8)1-6(13,5(11)12)2-4(9)10/h2-4,7-16H,5-6,17-20H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key: InChIKey=LHAPNDAERSFWSC-UHFFFAOYSA-N

SMILES: C(=C(N(=O)=O)C1=CC=CC=C1)(C2=CC=C(OCCN3CCCC3)C=C2)C4=CC=C(OC)C=C4.C(CC(O)=O)(CC(O)=O)(C(O)=O)O

Synonyms:

• 1-(2-(p-(alpha-(p-Methoxyphenyl)-beta-nitrostyryl)phenoxy)ethyl) pyrrolidine monocitrate
• 1-(2-(p-(alpha-(p-Methoxyphenyl)-beta-nitrostyryl)phenoxy)ethyl)pyrrolidine citrate (1:1)
• 1-[2-(p-[a-(p-Methoxyphenyl)-β-nitrostyryl]-phenoxy)ethyl]pyrrolidine monocitrate
• 1-[2-[4-[2-(4-Methoxyphenyl)-1-nitro-2-phenylethenyl]phenoxy]ethyl]pyrrolidine monocitrate
• 1-[2-[p-[α-(p-Methoxyphenyl)-β-nitrostyryl]phenoxy]ethyl]pyrrollidine monocitrate
• Ai3-52826
• CI-628 citrate
• Ci-628
• Cn-55945-27
• Nitromifene citrate [USAN]
• Nsc 110407
• Parke davis CI-628
• Pyrrolidine, 1-(2-(4-(1-(4-methoxyphenyl)-2-nitro-2-phenylethenyl)phenoxy)ethyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• Pyrrolidine, 1-(2-(p-(alpha-(p-methoxyphenyl)-beta-nitrostyryl)phenoxy)ethyl)-, citrate (1:1) (8CI)
• Pyrrolidine, 1-[2-[p-[α-(p-methoxyphenyl)-β-nitrostyryl]phenoxy]ethyl]-, citrate
• Pyrrolidine, 1-[2-[p-[α-(p-methoxyphenyl)-β-nitrostyryl]phenoxy]ethyl]-, citrate (1:1)

Nitromifene Citrate

CAS: 5863-35-4

Nitromifene Citrate is a nonsteroidal estrogen antagonist most commonly used as a research tool in animal studies.

Formula: C₃₃H₃₆N₂O₁₁

Color and Shape: Solid

Molecular weight: 636.654

Ref: TM-T33688

Nitromifene Citrate (E/Z mixture)

Controlled Product

CAS: 5863-35-4

Applications Nitromifene citrate is a non-steroidal estrogen antagonist. It is structurally similar to Tamoxifen (T006000) which is a selective estrogen response modifier (SERM).
References Rudick, C., et al.: Endorcrinol., 144, 179 (2003); Sutherland, R., et al.: Nature, 267, 434 (1977)

Formula: C₃₃H₃₆N₂O₁₁

Color and Shape: Yellow To Orange

Molecular weight: 636.65

Ref: TR-N496700

Nitromifene citrate

CAS: 5863-35-4

Nitromifene citrate is a nonsteroidal drug that inhibits the enzyme fatty acid synthase, thereby preventing the production of prostaglandins. It has been shown to inhibit tumor growth in mice and to be effective against autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Nitromifene citrate also binds to neurokinin-1 receptor and inhibits tissue culture granulosa cells. This drug has been shown to have clinical significance in the treatment of breast cancer. Nitromifene citrate is metabolized by the liver and is taken up into the brain where it can affect brain functions, such as emotional behavior or memory. Nitromifene citrate is synthesized by cultured cells in vitro and has been used for research purposes in vivo.

Formula: C₃₃H₃₆N₂O₁₁

Purity: Min. 95%

Molecular weight: 636.6 g/mol

Ref: 3D-FAA86335