CAS 586410-08-4

CIS-3,4',5-TRIMETHOXY-3'-HYDROXYSTILBENE

Description:

Cis-3,4',5-trimethoxy-3'-hydroxystilbene is a synthetic organic compound belonging to the stilbene family, characterized by its unique structural features that include multiple methoxy groups and a hydroxyl group. This compound exhibits a cis configuration, which influences its spatial arrangement and potentially its biological activity. The presence of three methoxy groups enhances its lipophilicity, which may affect its solubility and interaction with biological membranes. The hydroxyl group contributes to its potential as a phenolic compound, which can exhibit antioxidant properties. This compound has garnered interest in various fields, including medicinal chemistry and pharmacology, due to its potential therapeutic effects, including anti-inflammatory and anticancer activities. Its specific interactions and mechanisms of action, however, require further investigation to fully understand its biological implications. As with many stilbene derivatives, the compound's stability, reactivity, and biological efficacy can be influenced by environmental factors such as pH and temperature.

Formula: C₁₇H₁₈O₄

Synonyms:

• CIS-3,4',5-TRIMETHOXY-3'-HYDROXYSTILBENE
• CAY10616
• 5-[(1Z)-2-(3,5-Dimethoxyphenyl)ethenyl]-2-methoxy-phenol

cis-3,4',5-Trimethoxy-3'-hydroxystilbene

CAS: 586410-08-4

cis-3,4',5-Trimethoxy-3'-hydroxystilbene

Purity: 98%

Molecular weight: 286.32g/mol

Ref: 54-OR1075863

cis-3,4',5-Trimethoxy-3'-hydroxystilbene

Controlled Product

CAS: 586410-08-4

Applications A derivative of Resveratrol which shows apoptotic activity at nanomolar concentrations. Has an IC50= 0.3. It showed activity toward resistant HL60R cells and their activity was higher than that of several classic chemotherapeutic agents.
References Roberti, M., et al.: J. Med. Chem., 46, 3546 (2003)

Formula: C₁₇H₁₈O₄

Color and Shape: Neat

Molecular weight: 286.32

Ref: TR-T795680

cis-3,4',5-Trimethoxy-3'-hydroxystilbene

CAS: 586410-08-4

3,4',5-Trimethoxy-3'-hydroxystilbene is a natural compound that has been found to inhibit the growth of cancer cells in tumor xenografts. It also inhibits the activation of endothelial cells by stimulating the production of nitric oxide and prostacyclin. 3,4',5-Trimethoxy-3'-hydroxystilbene interacts with histone H3 and inhibits protein synthesis, making it a potential drug for cancer therapy. It also has bioreductive properties that may be useful in cancer treatment.

Formula: C₁₇H₁₈O₄

Purity: Min. 95%

Molecular weight: 286.32 g/mol

Ref: 3D-FT28521

cis-3,4',5-Trimethoxy-3'-hydroxystilbene

CAS: 586410-08-4

Cis-3,4',5-Trimethoxy-3'-hydroxystilbene, a stilbene derivative, induces apoptosis through the mitochondrial release of cytochrome c and suppresses tubulin polymerization. It is also noted for its application in leukemic research [1].

Formula: C₁₇H₁₈O₄

Color and Shape: Solid

Molecular weight: 286.327

Ref: TM-T84480