CAS 58652-20-3
:Nomegestrol acetate
Description:
Nomegestrol acetate is a synthetic progestin, primarily used in hormonal contraceptives and hormone replacement therapy. It is characterized by its ability to mimic the effects of natural progesterone, thereby regulating various physiological processes related to the menstrual cycle and pregnancy. The compound is typically administered orally and is known for its high oral bioavailability. Nomegestrol acetate exhibits anti-androgenic properties, making it effective in treating conditions like endometriosis and polycystic ovary syndrome. Its chemical structure includes a steroid backbone, which is essential for its biological activity. The substance is generally well-tolerated, though potential side effects may include weight gain, mood changes, and menstrual irregularities. As a progestin, it works by inhibiting ovulation, altering the endometrial lining, and thickening cervical mucus to prevent sperm penetration. Nomegestrol acetate is often combined with estrogen in contraceptive formulations to enhance efficacy and minimize side effects. Overall, its pharmacological profile makes it a valuable option in reproductive health management.
Formula:C23H30O4
InChI:InChI=1S/C23H30O4/c1-13-11-20-18(17-6-5-16(26)12-19(13)17)7-9-22(4)21(20)8-10-23(22,14(2)24)27-15(3)25/h11-12,17-18,20-21H,5-10H2,1-4H3/t17-,18-,20-,21+,22+,23+/m1/s1
InChI key:InChIKey=IIVBFTNIGYRNQY-YQLZSBIMSA-N
SMILES:C[C@@]12[C@@](OC(C)=O)(C(C)=O)CC[C@]1([C@]3([C@](CC2)([C@@]4(C(C(C)=C3)=CC(=O)CC4)[H])[H])[H])[H]
Synonyms:- (17Alpha)-17-Acetyl-6-Methyl-3-Oxoestra-4,6-Dien-17-Yl Acetate
- 17-(Acetyloxy)-6-methyl-19-norpregna-4,6-diene-3,20-dione
- 17-Hydroxy-6-Methyl-19-Norpregna-4,6-Diene-3,20-Dione 17-Acetate
- 19-Norpregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-methyl-
- 6-Methyl-17α-acetoxy-Δ<sup>6</sup>-19-norprogesterone
- Lutenyl
- Nomegestrol acetate
- Nomegestrol 17-acetate
- Normegestrol acetate
- Org 10486-0
- Surplant
- Tx 066
- Uniplant
- See more synonyms
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Found 10 products.
Nomegestrol Acetate
CAS:Formula:C23H30O4Color and Shape:White To Off-White SolidMolecular weight:370.49Nomegestrol Acetate
CAS:Formula:C23H30O4Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:370.49Nomegestrol acetate
CAS:<p>Nomegestrol acetate is a widely used progestin-like drug,which is characterized as a full agonist at the progesterone receptor</p>Formula:C23H30O4Purity:99.91%Color and Shape:SolidMolecular weight:370.48Nomegestrol Acetate
CAS:Controlled Product<p>Applications Progetin used in implantable hormone replacement therapies.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Vukusic, S., et al.: J. Neurol. Sci., 286, 114 (2009), Barbosa, I., et al.: Gynecol., Endocrinol., 25, 269 (2009),<br></p>Formula:C23H30O4Color and Shape:NeatMolecular weight:370.48Nomegestrol acetate
CAS:Controlled Product<p>Nomegestrol acetate is a nonsteroidal anti-inflammatory drug that binds to the response element of the gene, which leads to an increase in transcription. It is used in women to treat conditions such as endometriosis, menstrual disorders and breast cancer. The apoptosis pathway is activated by nomegestrol acetate by binding to the bcl-2 protein. This then causes a decrease in caspase activity, leading to cell death. Nomegestrol acetate also has been shown to have effects on ovarian activity and may be used as an analytical tool for determining the rate constant of polymerase chain reaction (PCR).</p>Formula:C23H30O4Purity:Min. 95%Molecular weight:370.48 g/mol
