CAS 58652-20-3

Nomegestrol acetate

Description:

Nomegestrol acetate is a synthetic progestin, primarily used in hormonal contraceptives and hormone replacement therapy. It is characterized by its ability to mimic the effects of natural progesterone, thereby regulating various physiological processes related to the menstrual cycle and pregnancy. The compound is typically administered orally and is known for its high oral bioavailability. Nomegestrol acetate exhibits anti-androgenic properties, making it effective in treating conditions like endometriosis and polycystic ovary syndrome. Its chemical structure includes a steroid backbone, which is essential for its biological activity. The substance is generally well-tolerated, though potential side effects may include weight gain, mood changes, and menstrual irregularities. As a progestin, it works by inhibiting ovulation, altering the endometrial lining, and thickening cervical mucus to prevent sperm penetration. Nomegestrol acetate is often combined with estrogen in contraceptive formulations to enhance efficacy and minimize side effects. Overall, its pharmacological profile makes it a valuable option in reproductive health management.

Formula: C₂₃H₃₀O₄

InChI: InChI=1S/C23H30O4/c1-13-11-20-18(17-6-5-16(26)12-19(13)17)7-9-22(4)21(20)8-10-23(22,14(2)24)27-15(3)25/h11-12,17-18,20-21H,5-10H2,1-4H3/t17-,18-,20-,21+,22+,23+/m1/s1

InChI key: InChIKey=IIVBFTNIGYRNQY-YQLZSBIMSA-N

SMILES: C[C@@]12[C@@](OC(C)=O)(C(C)=O)CC[C@]1([C@]3([C@](CC2)([C@@]4(C(C(C)=C3)=CC(=O)CC4)[H])[H])[H])[H]

Synonyms:

• (17Alpha)-17-Acetyl-6-Methyl-3-Oxoestra-4,6-Dien-17-Yl Acetate
• 17-(Acetyloxy)-6-methyl-19-norpregna-4,6-diene-3,20-dione
• 17-Hydroxy-6-Methyl-19-Norpregna-4,6-Diene-3,20-Dione 17-Acetate
• 19-Norpregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-methyl-
• 6-Methyl-17α-acetoxy-Δ⁶-19-norprogesterone
• Lutenyl
• Nomegestrol acetate
• Nomegestrol  17-acetate
• Normegestrol acetate
• Org 10486-0
• Surplant
• Tx 066
• Uniplant

NOMEGESTROL ACETATE FOR ID AND ASSAY CRS

CAS: 58652-20-3

NOMEGESTROL ACETATE FOR ID AND ASSAY CRS

Ref: 41-Y0002161

Nomegestrol acetate

CAS: 58652-20-3

Formula: C₂₃H₃₀O₄

Molecular weight: 370.48

Ref: 7W-GP9845

Nomegestrol Acetate

CAS: 58652-20-3

Formula: C₂₃H₃₀O₄

Color and Shape: White To Off-White Solid

Molecular weight: 370.49

Ref: 4Z-N-057002

Nomegestrol acetate

CAS: 58652-20-3

Nomegestrol acetate

Purity: ≥98%

Molecular weight: 370.48g/mol

Ref: 54-BUP09698

Nomegestrol Acetate

CAS: 58652-20-3

Formula: C₂₃H₃₀O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 370.49

Ref: 3B-N1277

Nomegestrol acetate

CAS: 58652-20-3

Nomegestrol acetate is a widely used progestin-like drug,which is characterized as a full agonist at the progesterone receptor

Formula: C₂₃H₃₀O₄

Purity: 99.91%

Color and Shape: Solid

Molecular weight: 370.48

Ref: TM-T8395

Nomegestrol Acetate-d6

CAS: 58652-20-3

Formula: C₂₃H₂₄D₆O₄

Molecular weight: 376.53

Ref: 4Z-N-057004

Nomegestrol Acetate

Controlled Product

CAS: 58652-20-3

Applications Progetin used in implantable hormone replacement therapies.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Vukusic, S., et al.: J. Neurol. Sci., 286, 114 (2009), Barbosa, I., et al.: Gynecol., Endocrinol., 25, 269 (2009),

Formula: C₂₃H₃₀O₄

Color and Shape: Neat

Molecular weight: 370.48

Ref: TR-N635855

Nomegestrol acetate

Controlled Product

CAS: 58652-20-3

Nomegestrol acetate is a nonsteroidal anti-inflammatory drug that binds to the response element of the gene, which leads to an increase in transcription. It is used in women to treat conditions such as endometriosis, menstrual disorders and breast cancer. The apoptosis pathway is activated by nomegestrol acetate by binding to the bcl-2 protein. This then causes a decrease in caspase activity, leading to cell death. Nomegestrol acetate also has been shown to have effects on ovarian activity and may be used as an analytical tool for determining the rate constant of polymerase chain reaction (PCR).

Formula: C₂₃H₃₀O₄

Purity: Min. 95%

Molecular weight: 370.48 g/mol

Ref: 3D-FN26400

Nomegestrol Acetate

CAS: 58652-20-3

Formula: C₂₃H₃₀O₄

Molecular weight: 370.49

Ref: ST-EA-CP-N99002