CAS 58691-88-6
:Nomegestrol
Description:
Nomegestrol is a synthetic progestin, primarily used in hormonal contraceptives and hormone replacement therapy. It is characterized by its ability to mimic the effects of natural progesterone, thereby regulating various physiological processes related to the menstrual cycle and pregnancy. Nomegestrol exhibits high oral bioavailability and is known for its selective action on progesterone receptors, which contributes to its efficacy in preventing ovulation and maintaining the uterine lining. The substance is typically administered in the form of tablets and is often combined with estrogen in contraceptive formulations. Its pharmacological profile includes anti-androgenic properties, making it beneficial in treating conditions like endometriosis and polycystic ovary syndrome. Nomegestrol's safety profile is generally favorable, but, like all hormonal therapies, it may be associated with side effects such as mood changes, weight gain, or increased risk of thromboembolic events. Overall, Nomegestrol is a significant compound in reproductive health, offering various therapeutic applications while necessitating careful consideration of its benefits and risks.
Formula:C21H28O3
InChI:InChI=1S/C21H28O3/c1-12-10-18-16(15-5-4-14(23)11-17(12)15)6-8-20(3)19(18)7-9-21(20,24)13(2)22/h10-11,15-16,18-19,24H,4-9H2,1-3H3/t15-,16-,18-,19+,20+,21+/m1/s1
InChI key:InChIKey=KZUIYQJTUIACIG-YBZCJVABSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@@]4(C(C(C)=C3)=CC(=O)CC4)[H])(CC1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]
Synonyms:- (17Alpha)-17-Acetyl-17-Hydroxy-6-Methylestra-4,6-Dien-3-One
- 17-Hydroxy-6-methyl-19-nor-4,6-pregnadiene-3,20-dione
- 17-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione
- 19-Norpregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-
- Monaco
- Nomegestrol [INN]
- Nomegestrolum
- Nomegestrolum [Latin]
- Thermex
- Tx 071
- Unii-10F89177Co
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 9 products.
19-Norpregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-
CAS:Formula:C21H28O3Purity:95%Color and Shape:SolidMolecular weight:328.4452Nomegestrol
CAS:Nomegestrol(TX 066 free base) is a full agonist of the progesterone receptor with strong anti-estrogenic, partial anti-androgenic and anti-gonadotropic activityFormula:C21H28O3Purity:98%Color and Shape:SolidMolecular weight:328.45Nomegestrol
CAS:Controlled Product<p>Applications A progestogen, derivatives of which are used in contraceptives and hormone therapies.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Catalano, D., et al.: Climacter., 11, 373 (2008), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008),<br></p>Formula:C21H28O3Color and Shape:NeatMolecular weight:328.45Nomegestrol
CAS:Controlled ProductNomegestrol acetate is a nonsteroidal anti-inflammatory drug that binds to cyclic nucleotide phosphodiesterases and inhibits their activity. This prevents the breakdown of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), which are second messengers in the cell that regulate many physiological processes. Nomegestrol acetate has been shown to inhibit ovarian activity, suppress ovulation, and decrease the production of progesterone. It also acts as a contraceptive by preventing implantation of the fertilized egg into the uterus.Formula:C21H28O3Purity:Min. 95%Molecular weight:328.45 g/mol
