CAS 58749-22-7: Licochalcone A
Description:Licochalcone A is a natural compound classified as a chalcone, primarily derived from the roots of the licorice plant, Glycyrrhiza inflata. It is known for its diverse biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties. The molecular formula of Licochalcone A is C15H12O4, and it features a characteristic structure that includes two aromatic rings connected by a three-carbon α,β-unsaturated carbonyl system. This compound has garnered interest in pharmacological research due to its potential therapeutic effects, particularly in skin health, where it has been studied for its ability to inhibit melanin production and reduce hyperpigmentation. Additionally, Licochalcone A exhibits potential in cancer research, as it has shown the ability to induce apoptosis in various cancer cell lines. Its solubility is generally higher in organic solvents than in water, which can influence its bioavailability and application in formulations. Overall, Licochalcone A represents a promising candidate for further exploration in medicinal chemistry and natural product research.
Formula:C21H22O4
InChI:InChI=1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+
InChI key:InChIKey=KAZSKMJFUPEHHW-DHZHZOJOSA-N
SMILES:O=C(C=CC1=CC(=C(O)C=C1OC)C(C=C)(C)C)C2=CC=C(O)C=C2
- Synonyms:
- (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
- (2E)-3-[5-(1,1-Dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one
- (2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
- 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-
- 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (E)-
- 2-propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-
- Licochalcone-A
- Licochalcone A