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CAS 5875-06-9

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Proparacaine hydrochloride

Description:
Proparacaine hydrochloride is a local anesthetic commonly used in ophthalmology for procedures requiring temporary loss of sensation in the eye. It belongs to the ester class of local anesthetics and is characterized by its rapid onset and relatively short duration of action. The chemical structure of proparacaine includes an aromatic ring, an ester linkage, and a tertiary amine, which contribute to its anesthetic properties. As a hydrochloride salt, it is typically presented as a white crystalline powder that is soluble in water, facilitating its use in aqueous solutions for eye drops. Proparacaine acts by blocking sodium channels in nerve membranes, thereby inhibiting the propagation of nerve impulses. It is generally well-tolerated, although potential side effects may include transient stinging or burning upon application, as well as rare allergic reactions. Due to its effectiveness and safety profile, proparacaine hydrochloride is widely utilized in various ophthalmic procedures, including tonometry and cataract surgery.
Formula:C16H26N2O3·ClH
InChI:InChI=1S/C16H26N2O3.ClH/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3;/h7-8,12H,4-6,9-11,17H2,1-3H3;1H
InChI key:InChIKey=BFUUJUGQJUTPAF-UHFFFAOYSA-N
SMILES:C(OCCN(CC)CC)(=O)C1=CC(N)=C(OCCC)C=C1.Cl
Synonyms:
  • 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate hydrochloride
  • 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate monohydrochloride
  • 2-[(3-amino-4-propoxybenzoyl)oxy]-N,N-diethylethanaminium chloride
  • Ak-Taine
  • Alcaine
  • Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, hydrochloride (1:1)
  • Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride
  • Chibro-keracaine
  • Fluoracaine
  • Ophthain
  • See more synonyms
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