CAS 5878-43-3

(8β)-6-Methylergoline-8-carboxylic acid

Description:

(8β)-6-Methylergoline-8-carboxylic acid, with the CAS number 5878-43-3, is a chemical compound belonging to the ergoline family, which is characterized by a tetracyclic structure derived from the alkaloid ergoline. This compound features a methyl group at the 6-position and a carboxylic acid functional group at the 8-position, contributing to its unique chemical properties. Ergoline derivatives are known for their biological activity, often interacting with various neurotransmitter receptors, which can lead to a range of pharmacological effects. The presence of the carboxylic acid group suggests potential for solubility in polar solvents and reactivity in organic synthesis. Additionally, the stereochemistry indicated by the (8β) designation implies specific spatial arrangements that can influence the compound's interactions and biological activity. Overall, (8β)-6-Methylergoline-8-carboxylic acid is of interest in both medicinal chemistry and pharmacology, particularly in the study of compounds that affect the central nervous system.

Formula: C₁₆H₁₈N₂O₂

InChI: InChI=1S/C16H18N2O2/c1-18-8-10(16(19)20)5-12-11-3-2-4-13-15(11)9(7-17-13)6-14(12)18/h2-4,7,10,12,14,17H,5-6,8H2,1H3,(H,19,20)/t10-,12-,14-/m1/s1

InChI key: InChIKey=ORBSYPFBZQJNJE-MPKXVKKWSA-N

SMILES: CN1[C@]2([C@@](C=3C=4C(C2)=CNC4C=CC3)(C[C@@H](C(O)=O)C1)[H])[H]

Synonyms:

• (8Beta,10Xi)-6-Methylergoline-8-Carboxylic Acid
• (8β)-6-Methylergoline-8-carboxylic acid
• 6-Methyl-8β-carboxyergoline
• 6-Methyl-8β-ergolinecarboxylic acid
• 6-Methylergoline-8beta-carboxylic acid
• 9,10-Dihydro-<span class="text-smallcaps">D</span>-lysergic acid
• 9,10-Dihydrolysergic acid
• 9,10-Dihydrolysergic acid I
• 9,10α-Dihydrolysergic acid
• <span class="text-smallcaps">D</span>-Dihydrolysergic acid I
• Dihydrolysergic acid
• Ergoline-8-carboxylic acid, 6-methyl-, (8β)-
• Ergoline-8β-carboxylic acid, 6-methyl-
• Lysergic acid, 9,10-dihydro-, I

Dihydrolysergic Acid

CAS: 5878-43-3

Formula: C₁₆H₁₈N₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 270.33

Ref: 4Z-E-6115

Dihydrolysergic Acid

Controlled Product

CAS: 5878-43-3

Stability Hygroscopic
Applications Dihydrolysergic Acid is an metabolite of Erogtamine (E599500), an antimigraine agent used in combination with caffeine (C080100).
References Marzoni, G., et al.: Synthesis., 7, 651 (1987);

Formula: C₁₆H₁₈N₂O₂

Color and Shape: Neat

Molecular weight: 270.33

Ref: TR-D448795

Dihydrolysergic Acid

CAS: 5878-43-3

Formula: C₁₆H₁₈N₂O₂

Molecular weight: 270.3

Ref: ST-EA-CP-D107014