CAS 58786-99-5

Butorphanol tartrate

Description:

Butorphanol tartrate is a synthetic opioid analgesic primarily used for pain management. It is classified as a mixed agonist-antagonist, meaning it can activate certain opioid receptors while simultaneously blocking others, which can help reduce the risk of dependence and respiratory depression associated with traditional opioids. The substance is typically administered via injection or nasal spray and is known for its relatively rapid onset of action. Butorphanol tartrate exhibits a higher affinity for the kappa-opioid receptor compared to the mu-opioid receptor, contributing to its analgesic effects. It is also characterized by its solubility in water, which facilitates its formulation for medical use. Common side effects may include sedation, dizziness, and nausea, and it is important to monitor patients for potential adverse reactions. Due to its opioid nature, butorphanol tartrate is classified as a controlled substance in many jurisdictions, necessitating careful prescribing and dispensing practices.

Formula: C₂₁H₂₉NO₂·C₄H₆O₆

InChI: InChI=1S/C21H29NO2.C4H6O6/c23-17-7-6-16-12-19-21(24)9-2-1-8-20(21,18(16)13-17)10-11-22(19)14-15-4-3-5-15;5-1(3(7)8)2(6)4(9)10/h6-7,13,15,19,23-24H,1-5,8-12,14H2;1-2,5-6H,(H,7,8)(H,9,10)/t19-,20+,21-;1-,2-/m10/s1

InChI key: InChIKey=GMTYREVWZXJPLF-AFHUBHILSA-N

SMILES: O[C@@]12[C@@]3(C=4C(C[C@]1(N(CC5CCC5)CC3)[H])=CC=C(O)C4)CCCC2.[C@H]([C@@H](C(O)=O)O)(C(O)=O)O

Synonyms:

• 17-(Cyclobutylmethyl)Morphinan-3,14-Diol 2,3-Dihydroxybutanedioate (Salt)
• 17-(Cyclobutylmethyl)Morphinan-3,14-Diol 2,3-Dihydroxybutanedioate (1:1)
• [S-(R*,R*)]-2,3-dihidroxisuccinato de 17-(ciclobutilmetil)morfinan-3,14-diilo
• [S-(R*,R*)]-2,3-dihydroxysuccinate de 17-(cyclobutylmethyl)morphinan-3,14-diyle
• 17-(cyclobutylmethyl)morphinan-3,14-diyl [S-(R*,R*)]-2,3-dihydroxysuccinate
• 17-(Cyclobutylmethyl)morphinan-3,14-diyl-[S-(R*,R*)]-2,3-dihydroxysuccinat
• Butorphanol tartrate
• Butorphic
• l-Butorphanol tartrate
• Levo-BC 2627 tartrate
• Moradol
• Morphinan-3,14-diol, 17-(cyclobutylmethyl)-, (2S,3S)-2,3-dihydroxybutanedioate (1:1)
• Morphinan-3,14-diol, 17-(cyclobutylmethyl)-, (2S,3S)-2,3-dihydroxybutanedioate (1:1) (salt)
• Morphinan-3,14-diol, 17-(cyclobutylmethyl)-, [S-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt)
• Nih 10275
• Stadol
• Torate

Butorphanol Tartrate 1.0 mg/ml in Methanol (as free base)

CAS: 58786-99-5

Color and Shape: Single Solution

Ref: 61-AMP1192.00-01

Butorphanol Tartrate

CAS: 58786-99-5

Color and Shape: Neat

Ref: 61-FOR1192.00

Butorphanol tartrate

Controlled Product

CAS: 58786-99-5

Color and Shape: Neat

Ref: 04-C10896000

Butorphanol Tartrate

Controlled Product

CAS: 58786-99-5

Formula: C₂₁H₂₉NO₂·C₄H₆O₆

Color and Shape: Neat

Molecular weight: 477.55

Ref: 86-MM1192.00

Butorphanol tartrate

Controlled Product

CAS: 58786-99-5

Butorphanol tartrate is a pharmaceutical drug that can be used to diagnose the causes of pain. It is used in the treatment of moderate to severe pain, as well as for post-operative and cancer pain relief. Butorphanol tartrate binds with high affinity to opioid receptors, including κ-opioid receptors and the serotonin transporter gene (SERT). This binding prevents the reuptake of serotonin into presynaptic neurons, leading to increased levels of serotonin in the synapse. This increased level of serotonin can inhibit the production of fatty acids in fat cells, which are responsible for regulating blood pressure. Butorphanol tartrate also has an effect on chloride channels, which can lead to an increase in chloride ions inside neurons. It is interesting to note that butorphanol tartrate does not appear to have any effect on β-adrenergic receptors or sodium channels.

Formula: C₂₅H₃₅NO₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 477.55 g/mol

Ref: 3D-ICA78699

Butorphanol Tartrate CIV

Controlled Product

CAS: 58786-99-5

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Formula: C₂₁H₂₉NO₂·C₄H₆O₆

Color and Shape: White Powder

Molecular weight: 477.55

Ref: 45-1082504