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CAS 587880-86-2

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FMOC-AZA-L-LEUCINE

Description:
FMOC-AZA-L-LEUCINE is a synthetic amino acid derivative characterized by the presence of a 9-fluorenylmethoxycarbonyl (FMOC) protecting group attached to the azole derivative of L-leucine. This compound is primarily utilized in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the FMOC group serves as a protective moiety that can be easily removed under mild basic conditions. The azole modification enhances the compound's stability and solubility, making it suitable for various biochemical applications. FMOC-AZA-L-LEUCINE exhibits properties typical of amino acids, including the ability to form peptide bonds, and it contributes to the overall hydrophobic character of peptides due to the leucine side chain. Its unique structure allows for the incorporation of azole functionalities, which can impart specific biological activities or enhance interactions in peptide-based therapeutics. As with many synthetic amino acids, careful handling and storage are recommended to maintain its integrity and reactivity in chemical reactions.
Formula:C20H22N2O4
Synonyms:
  • FMOC-L-2-AMINO-3-(DIMETHYLAMINO)PROPIONIC ACID
  • FMOC-(S)-2-AMINO-3-(DIMETHYLAMINO)PROPANOIC ACID
  • L-Alanine, 3-(dimethylamino)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • Fmoc-L-Dap(Me)2-OH
  • FMOC-BETA-N,N-DIMETHYLAMINO-L-ALA
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(dimethylamino)propanoic acid
  • (2S)-3-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • FMOC-AZA-L-LEUCINE
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