CAS 588-36-3

[4-amino-2-(methylsulfanyl)pyrimidin-5-yl]methanol

Description:

[4-amino-2-(methylsulfanyl)pyrimidin-5-yl]methanol, with the CAS number 588-36-3, is a chemical compound that belongs to the class of pyrimidines, which are heterocyclic aromatic organic compounds. This substance features a pyrimidine ring substituted with an amino group and a methylthio group, as well as a hydroxymethyl group. The presence of the amino group contributes to its basicity, while the methylthio group can influence its reactivity and solubility in various solvents. The hydroxymethyl group enhances its potential for hydrogen bonding, which can affect its interactions in biological systems. This compound may exhibit biological activity, making it of interest in medicinal chemistry and drug development. Its structural characteristics suggest potential applications in pharmaceuticals, particularly in the development of compounds targeting specific biological pathways. As with many organic compounds, its stability, solubility, and reactivity can vary based on environmental conditions and the presence of other chemical species.

Formula: C₆H₉N₃OS

InChI: InChI=1/C6H9N3OS/c1-11-6-8-2-4(3-10)5(7)9-6/h2,10H,3H2,1H3,(H2,7,8,9)

SMILES: CSc1ncc(CO)c(=N)[nH]1

Synonyms:

• 4-Amino-2-methylmercapto-5-pyrimidinemethanol
• 4-Amino-2-methylthio-5-pyrimidinemethanol
• 4-Amino-5-hydroxymethyl-2-methylthiopyrimidine
• 5-Pyrimidinemethanol, 4-amino-2-(methylthio)-
• (4-Amino-2-(methylthio)pyrimidin-5-yl)methanol

(4-amino-2-(methylthio)pyrimidin-5-yl)methanol

CAS: 588-36-3

Formula: C₆H₉N₃OS

Purity: 95%

Color and Shape: Solid

Molecular weight: 171.2202

Ref: IN-DA00EBQI

4-Amino-5-hydroxymethyl-2-(methylthio)pyrimidine

CAS: 588-36-3

4-Amino-5-hydroxymethyl-2-(methylthio)pyrimidine

Purity: 97%

Molecular weight: 171.23g/mol

Ref: 54-OR75285

4-Amino-5-hydroxymethyl-2-(methylthio)pyrimidine

CAS: 588-36-3

Formula: C₆H₉N₃OS

Purity: 97%

Molecular weight: 171.22

Ref: 10-F217463

Methioprim

Controlled Product

CAS: 588-36-3

Applications An intermediate used in the synthesis of Thiamine (T344185). Also, used for the preparation of pyridopyrimidines and naphthyridines as inhibitors of Akt kinase for the treatment of cancer.
References Zinda, M., et al.: Clin. Cancer Res., 7, 2475 (2001), Breitenlechner, C., et al.: J. Med. Chem., 47, 1375 (2004), Zhao, Z., et al.: Bioorg. Med. Chem. Lett., 18, 49 (2008),

Formula: C₆H₉N₃OS

Color and Shape: Neat

Molecular weight: 171.22

Ref: TR-M260520