CAS 58842-20-9

Nithiazine

Description:

Nithiazine is a chemical compound classified as a thiazine derivative, primarily recognized for its use in veterinary medicine as an anthelmintic agent, particularly for the treatment of parasitic infections in livestock. It exhibits a broad spectrum of activity against various helminths and is known for its efficacy in controlling parasitic diseases. The compound has a unique molecular structure that contributes to its pharmacological properties, including its ability to interfere with the metabolic processes of parasites. Nithiazine is typically administered in specific dosages, and its safety profile has been evaluated in various studies, indicating a favorable therapeutic index when used appropriately. However, like many pharmaceuticals, it may have potential side effects and contraindications, necessitating careful consideration in its application. Additionally, its environmental impact and residue management in food-producing animals are important factors in its use. Overall, Nithiazine represents a significant tool in veterinary parasitology, contributing to animal health and productivity.

Formula: C₅H₈N₂O₂S

InChI: InChI=1S/C5H8N2O2S/c8-7(9)4-5-6-2-1-3-10-5/h4,6H,1-3H2

InChI key: InChIKey=LZTIMERBDGGAJD-UHFFFAOYSA-N

SMILES: C(N(=O)=O)=C1NCCCS1

Synonyms:

• SD 35651
• Tetrahydro-2-(nitromethylene)-2H-1,3-thiazine
• WL 35651
• TTNM
• 2H-1,3-Thiazine, tetrahydro-2-(nitromethylene)-

Nithiazine

CAS: 58842-20-9

Formula: C₅H₈N₂O₂S

Molecular weight: 160.19

Ref: 4Z-N-142001

Nithiazine

Controlled Product

CAS: 58842-20-9

Applications Nithiazine is a useful building block and insecticide.
References Quaranta, L.; et al.: WO 2018149851 (2018).

Formula: C₅H₈N₂O₂S

Color and Shape: Neat

Molecular weight: 160.194

Ref: TR-N561200

2-(Nitromethylidene)-1,3-thiazinane

CAS: 58842-20-9

2-(Nitromethylidene)-1,3-thiazinane is a chemical compound that has been shown to have chronic toxic effects in animal studies. It binds to the ryanodine receptor and inhibits the release of calcium from the sarcoplasmic reticulum, which may lead to an increase in acetylcholine, a neurotransmitter involved in many aspects of brain function. 2-(Nitromethylidene)-1,3-thiazinane has also been shown to inhibit the activity of neonicotinoids, insecticides that are used for agricultural and veterinary purposes. This compound is structurally similar to other non-competitive inhibitors of acetylcholine esterase, such as piperonyl butoxide.

Formula: C₅H₈N₂O₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 160.2 g/mol

Ref: 3D-ICA84220