CAS 588691-24-1

5'-O-DMT-5-I-2'-OME-RU

Description:

5'-O-DMT-5-I-2'-OME-RU, with the CAS number 588691-24-1, is a chemical compound that belongs to the class of nucleoside analogs. It features a 5'-dimethoxytrityl (DMT) protecting group, which is commonly used in the synthesis of oligonucleotides to protect the hydroxyl group at the 5' position. The presence of iodine at the 5 position indicates potential reactivity and may influence the compound's biological activity. The 2'-O-methyl (OME) modification enhances the stability of the nucleoside against enzymatic degradation, making it more suitable for therapeutic applications. This compound is typically utilized in research settings, particularly in the fields of molecular biology and medicinal chemistry, where it may serve as a building block for the synthesis of modified RNA or DNA sequences. Its unique structural features contribute to its potential utility in various applications, including gene therapy and the development of novel therapeutics. As with any chemical substance, proper handling and safety protocols should be observed during its use.

Formula: C₃₁H₃₁IN₂O₈

Synonyms:

• 5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-O-METHYLURIDINE
• 5-I-DMT-2'-O-Me-Ur
• Uridine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-5-iodo-2'-O-Methyl-
• Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-iodo-2'-O-methyl- (9CI)
• 5'-O-(DMT)-5-IODO-2'-O-METHYLURIDINE
• 2'-O-Methyl-5'-O-DMT-5-iodouridine
• 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-iodo-2'-O-methyl-uridine
• 2’-O-Methyl-5’-O-(4,4’-dimethoxytrityl)-5-iodouridine
• 2'-O-Methyl-5'-O-DMTr-5-iodouridine
• 5'-O-(4,4'-Dimethoxytrityl)-5-Iodo-2'-O-Methyluridine

2'-O-Methyl-5'-O-DMT-5-iodouridine

CAS: 588691-24-1

Nucleoside, halo-nucleoside, 2’-O-Methyl nucleoside

Formula: C₃₁H₃₁IN₂O₈

Color and Shape: Solid

Molecular weight: 686.49

Ref: TM-TNU0631

5'-O-DMT-5-iodo-2'-O-methyluridine

CAS: 588691-24-1

5'-O-DMT-5-iodo-2'-O-methyluridine is an activator and antitumor agent that is used in the synthesis of 5'-O-DMT-5-iodo-2'-O-(2,4,6-trimethoxybenzoyl)uridine for cancer research. This chemical is a novel synthetic nucleoside with a high purity and quality that can be used to synthesize deoxyribonucleosides, nucleosides, and phosphoramidites. It has a CAS number of 588691-24-1. 5'-O-DMT-5-iodo-2'-O-(2,4,6 trimethoxybenzoyl)uridine can be used as an antiviral agent against HIV and other retroviruses.

Formula: C₃₁H₃₁IN₂O₈

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 686.49 g/mol

Ref: 3D-ND144586