CAS 58909-56-1

(6R,7R)-7-Amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Description:

The chemical substance known as (6R,7R)-7-Amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, with the CAS number 58909-56-1, is a complex organic compound that belongs to a class of molecules known for their potential pharmacological properties. This compound features a bicyclic structure, which contributes to its unique chemical reactivity and biological activity. The presence of amino and carboxylic acid functional groups suggests that it may exhibit polar characteristics, potentially influencing its solubility and interaction with biological systems. Additionally, the incorporation of a thioether and a triazine moiety indicates that it may have specific mechanisms of action, possibly related to antimicrobial or antiviral activities. Overall, this compound's intricate structure and functional groups make it a subject of interest in medicinal chemistry and drug development, warranting further investigation into its therapeutic potential and mechanisms of action.

Formula: C₁₂H₁₃N₅O₅S₂

InChI: InChI=1/C12H13N5O5S2/c1-16-12(14-7(18)8(19)15-16)24-3-4-2-23-10-5(13)9(20)17(10)6(4)11(21)22/h5,10H,2-3,13H2,1H3,(H,15,19)(H,21,22)/t5-,10-/m0/s1

InChI key: InChIKey=YTUNICCSPPTMJY-GPXNAGAYSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1CSC=3N(C)NC(=O)C(=O)N3)[H]

Synonyms:

• (6R,7R)-7-Amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6S,7S)-7-ammonio-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (7R)-7-amino-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, (6R-trans)-
• 7-Amino-3-[[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-1,2,4-triazin-3-yl)thio]methyl]cephalosporanic acid
• (6R-trans)-7-Amino-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
• 7-AMINOCEPHALOSPORANIC TRIAZINE
• Ceftriaxone EP Impurity E
• (6R,7R)-7-amino-3-(((2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Einecs 261-491-7
• DISCONTINUED
• (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid USP/EP/BP
• 7-Amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl
• 7-Amino-3-([2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3-y]thiomethyl)-3-cephem-4-carboxylic acid
• Ceftriaxone Sodium Ep Impurity E
• Ceftriaxone impurity 4/Ceftriaxone EP Impurity E/7-AMino-3-[[(2,5-dihydro-6-hydroxy-2-Methyl-5-oxo-1,2,4-triazin-3-yl)thio]Methyl]cephalosporanic Acid
• Ceftriaxone Impurity E USP/EP/BP
• (7R)-7-amino-3-(((6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Ceftriaxone EP Impurity E

CAS: 58909-56-1

Formula: C₁₂H₁₃N₅O₅S₂

Color and Shape: White To Off-White Solid

Molecular weight: 371.39

Ref: 4Z-C-936

7-Amino-3-[[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo- 1,2,4-triazin-3-yl)thio]methyl]cephalosporanic acid

CAS: 58909-56-1

Ceftriaxone is a semisynthetic, broad-spectrum antibiotic that is used to treat bacterial infections. It is especially effective against the following microorganisms: Gram-positive cocci and rods, Gram-positive bacilli, Gram-negative cocci and rods, and anaerobic bacteria. Ceftriaxone is a crystalline solid that can be dissolved in water or an organic solvent. It has been shown to have excellent stability in acidic solutions and at high temperatures. Ceftriaxone has a residue of 3% when it is administered intravenously or intramuscularly. The use of ceftriaxone as an antibiotic can be optimized by using reverse-phase chromatography with a cyclic gradient elution method.

Formula: C₁₂H₁₃N₅O₅S₂

Purity: 95%Nmr

Color and Shape: Powder

Molecular weight: 371.39 g/mol

Ref: 3D-FA17508

Ceftriaxone EP Impurity E

CAS: 58909-56-1

Formula: C₁₂H₁₃N₅O₅S₂

Molecular weight: 371.39

Ref: ST-EA-CP-C91005