CAS 5891-45-2

Z-Glu-OtBu

Description:

Z-Glu-OtBu, also known as Z-Glutamic acid tert-butyl ester, is a derivative of glutamic acid, an amino acid that plays a crucial role in various biological processes. This compound features a Z (benzyloxycarbonyl) protecting group on the amino group, which enhances its stability and solubility in organic solvents. The tert-butyl ester group provides a hydrophobic character, making it useful in peptide synthesis and other organic reactions. Z-Glu-OtBu is typically a white to off-white crystalline solid, and it is soluble in common organic solvents like dichloromethane and methanol. Its structure allows for selective reactions, particularly in the formation of peptides, where the protecting groups can be removed under specific conditions to yield the free amino acid. The compound is often utilized in research and pharmaceutical applications, particularly in the synthesis of bioactive peptides and as an intermediate in organic synthesis. Proper handling and storage are essential, as with many chemical substances, to ensure safety and maintain its integrity.

Formula: C₁₇H₂₃NO₆

InChI: InChI=1/C17H23NO6/c1-17(2,3)24-15(21)13(9-10-14(19)20)18-16(22)23-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,19,20)/t13-/m0/s1

SMILES: CC(C)(C)OC(=O)[C@H](CCC(=O)O)N=C(O)OCc1ccccc1

Synonyms:

• Cbz-L-glutamic acid 1-tert-butyl ester

1-tert-Butyl N-Carbobenzoxy-L-glutamate

CAS: 5891-45-2

Formula: C₁₇H₂₃NO₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 337.37

Ref: 3B-B4912

Z-Glu-OtBu

CAS: 5891-45-2

Bachem ID: 4029292.

Formula: C₁₇H₂₃NO₆

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 337.37

Ref: 01-4029292

Z-Glu-Otbu

CAS: 5891-45-2

Formula: C₁₇H₂₃NO₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 337.3676

Ref: IN-DA00EAXV

Z-Glu-Otbu

CAS: 5891-45-2

Z-Glu-Otbu

Purity: 98%

Molecular weight: 337.37g/mol

Ref: 54-OR1015450

N-(Benzyloxycarbonyl)-L-glutamic Acid α-tert-Butyl Ester

Controlled Product

CAS: 5891-45-2

Applications A protected glutamic acid for use in peptide synthesis.
References Takahashi, M., et al.: J. Exp. Biol., 200, 401 (1997), Michaelis, E., et al.: Prog. Neurobiol., 54, 369 (1998), Koch, H., et al.: Mol. Pharmacol., 55, 1044 (1999), O'Kane, R., et al.: J. Biol. Chem., 274, 31891 (1999),

Formula: C₁₇H₂₃NO₆

Color and Shape: Neat

Molecular weight: 337.368

Ref: TR-B286245

z-glu-otbu

CAS: 5891-45-2

Formula: C₁₇H₂₃NO₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 337.372

Ref: 10-F045479

Z-Glu-OtBu

CAS: 5891-45-2

Z-Glu-OtBu is a peptide synthesis inhibitor that has been used in solid-phase peptide synthesis. It prevents the formation of the carboxyl group in the penicillin-binding protein. Z-Glu-OtBu inhibits the formation of aldehydes and esters, which are involved in protein synthesis. This agent also mimics the c-terminal sequence of penicillin-binding proteins, preventing binding to bacterial cell walls by competitive inhibition.

Formula: C₁₇H₂₃NO₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 337.37 g/mol

Ref: 3D-FG41772