CAS 58955-94-5

rel-(10R,11S)-10,11-Dihydro-10,11-dihydroxy-5H-dibenz[b,f]azepine-5-carboxamide

Description:

Rel-(10R,11S)-10,11-Dihydro-10,11-dihydroxy-5H-dibenz[b,f]azepine-5-carboxamide, with CAS number 58955-94-5, is a chemical compound characterized by its complex bicyclic structure, which includes a dibenzazepine core. This compound features two hydroxyl (-OH) groups at the 10 and 11 positions, contributing to its potential reactivity and solubility in polar solvents. The presence of a carboxamide functional group enhances its ability to form hydrogen bonds, which may influence its biological activity and interactions with other molecules. The specific stereochemistry indicated by the (10R,11S) configuration suggests that the compound has distinct spatial arrangements that can affect its pharmacological properties. Such compounds are often studied for their potential therapeutic applications, particularly in the fields of neuroscience and psychiatry, due to their structural similarity to various neurotransmitter systems. Overall, this compound's unique structural features and functional groups make it a subject of interest in medicinal chemistry and drug development.

Formula: C₁₅H₁₄N₂O₃

InChI: InChI=1/C15H14N2O3/c16-15(20)17-11-7-3-1-5-9(11)13(18)14(19)10-6-2-4-8-12(10)17/h1-8,13-14,18-19H,(H2,16,20)/t13-,14+

InChI key: InChIKey=PRGQOPPDPVELEG-OKILXGFUNA-N

SMILES: C(N)(=O)N1C=2C([C@H](O)[C@H](O)C=3C1=CC=CC3)=CC=CC2

Synonyms:

• cis-10,11-Dihydro-10,11-dihydroxycarbamazepine
• 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10,11-dihydroxy-, cis-
• cis-10,11-Dihydroxy-10,11-dihydrocarbamazepine
• 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10,11-dihydroxy-, (10R,11S)-rel-
• rel-(10R,11S)-10,11-Dihydro-10,11-dihydroxy-5H-dibenz[b,f]azepine-5-carboxamide

Oxcarbazepine Impurity 14

CAS: 58955-94-5

Formula: C₁₅H₁₄N₂O₃

Molecular weight: 270.29

Ref: 4Z-O-0646

cis-Carbamazepin-10,11-dihydro-10,11-dihydroxide 100 µg/mL in Acetonitrile

CAS: 58955-94-5

Formula: C₁₅H₁₄N₂O₃

Color and Shape: Single Solution

Molecular weight: 270.28

Ref: 04-A10968520AL-100

cis-10,11-Dihydroxy-10,11-dihydrocarbamazepine

CAS: 58955-94-5

Applications cis-10,11-Dihydroxy-10,11-dihydrocarbamazepine is a Carbamazepine (C175840) metabolite. It can also be used for anti-epileptic drugs with biological relevant free radicals.
References Laurentiis, E. et al.: Environ. Sci. Technol., 46, 8164 (2012); Ijiri, Y. et al.: J. Appl. Ther. Res., 2, 281 (1999); Lertratanangkoon, K. & Horning, M.G.: Drug Metab. Dispos., 10, 1 (1982); Martins, I.L., et.al., Free Radic. Biol. Med., 129, 559-568, (2018);

Formula: C₁₅H₁₄N₂O₃

Color and Shape: Neat

Molecular weight: 270.28

Ref: TR-D448815

Cis-10,11-dihydroxy-10,11-dihydrocarbamazepine

CAS: 58955-94-5

Cis-10,11-dihydroxy-10,11-dihydrocarbamazepine is a drug that is used to treat epilepsy. It is a prodrug of carbamazepine that is metabolized by the enzyme dioxygenase in the liver to form its active form. Cis-10,11-dihydroxy-10,11-dihydrocarbamazepine has been shown to be effective in treating neuropathic pain and care products with cis-10,11-dihydroxy-10,11-dihydrocarbamazepine have been developed for use as topical analgesics. Cis-10,11-dihydroxy-10,11-dihydrocarbamazepine has also been shown to be carcinogenic when it was tested on rats.

Formula: C₁₅H₁₄N₂O₃

Purity: Min. 95%

Molecular weight: 270.28 g/mol

Ref: 3D-ICA95594

Oxcarbazepine Impurity 14

CAS: 58955-94-5

Formula: C₁₅H₁₄N₂O₃

Molecular weight: 270.29

Ref: ST-EA-CP-O13041