CAS 5897-19-8

Cyclizine lactate

Description:

Cyclizine lactate, with the CAS number 5897-19-8, is a chemical compound that belongs to the class of antihistamines, specifically a piperazine derivative. It is primarily used for its antiemetic properties, helping to prevent and treat nausea and vomiting associated with motion sickness and other conditions. Cyclizine lactate exhibits a moderate affinity for histamine H1 receptors, which contributes to its effectiveness in alleviating symptoms related to motion sickness. The compound is typically administered in the form of its lactate salt, which enhances its solubility and bioavailability. In terms of physical characteristics, cyclizine lactate is usually presented as a white to off-white crystalline powder. It is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. Additionally, cyclizine lactate may have side effects common to antihistamines, such as drowsiness, dry mouth, and dizziness. As with any medication, it is important to use cyclizine lactate under the guidance of a healthcare professional to ensure safety and efficacy.

Formula: C₂₁H₂₈N₂O₃

InChI: InChI=1/C18H22N2.C3H6O3/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17;1-2(4)3(5)6/h2-11,18H,12-15H2,1H3;2,4H,1H3,(H,5,6)

InChI key: InChIKey=JOROEVAWQLGPFQ-UHFFFAOYSA-N

SMILES: C(N1CCN(C)CC1)(C2=CC=CC=C2)C3=CC=CC=C3.C(C(O)=O)(C)O

Synonyms:

• 1-(Diphenylmethyl)-4-methylpiperazine monolactate
• 1-Benzhydryl-4-methylpiperazine 2-hydroxypropanoate
• 2-Hydroxypropanoic Acid - 1-(Diphenylmethyl)-4-Methylpiperazine (1:1)
• Bw 4783
• Cyclizine lactate [USAN:BAN]
• Lactic acid, compd. with 1-(diphenylmethyl)-4-methylpiperazine (1:1)
• Lactic acid, salt with 1-diphenylmethyl-4-methylpiperazine
• Piperazine, 1-(diphenylmethyl)-4-methyl-, mono(2-hydroxypropanoate)
• Piperazine, 1-(diphenylmethyl)-4-methyl-, monolactate
• Propanoic acid, 2-hydroxy-, compd. with 1-(diphenylmethyl)-4-methylpiperazine (1:1)
• Unii-861R00J986
• Valoid
• Cyclizine lactate
• 1-benzhydryl-4-methylpiperazine,2-hydroxypropanoicaci

Cyclizine Lactate

Controlled Product

CAS: 5897-19-8

Applications Cyclizine Lactate is a lactate salt of Cyclizine (C987805, HCl salt) which is a piperazine derivative with anti-emetic activity that is useful in the prevention and treatment of nausea and vomiting associated with motion sickness.
References Kuntzman, R., et al.: J. Pharmacol. Exp. Ther., 158, 332 (1967), Walker, R., et al.: Eur. J. Pharm. Sci., 4, 301 (1996), Dumasia, M., et al.: Xenobiotica, 32, 795 (2002)

Formula: C₂₁H₂₈N₂O₃

Color and Shape: Neat

Molecular weight: 356.46

Ref: TR-C987440

Cyclizine-d4 Lactate

Controlled Product

CAS: 5897-19-8, 82-92-8

Formula: C₂₁H₂₄D₄N₂O₃

Color and Shape: Neat

Molecular weight: 357.459

Ref: TR-C987442