CAS 59-26-7: Tocainide
Description:Tocainide is a pharmaceutical compound primarily used as an antiarrhythmic agent, particularly in the treatment of ventricular arrhythmias. It belongs to the class of drugs known as sodium channel blockers, which work by inhibiting the influx of sodium ions during the depolarization phase of the cardiac action potential, thereby stabilizing the cardiac membrane and reducing abnormal electrical activity. Tocainide is characterized by its chemical formula, which includes a piperidine ring, and it is typically administered orally. The substance has a moderate solubility in water and is known for its relatively low toxicity compared to other antiarrhythmic agents. Tocainide's pharmacokinetics involve hepatic metabolism, and it is excreted primarily through the kidneys. While effective, its use may be limited by side effects such as gastrointestinal disturbances and potential for blood dyscrasias. Due to these factors, monitoring is essential during treatment. Overall, Tocainide represents an important option in the management of certain cardiac arrhythmias, although its clinical use has diminished with the advent of newer agents.
Formula:C10H14N2O
InChI:InChI=1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3
InChI key:InChIKey=NCYVXEGFNDZQCU-UHFFFAOYSA-N
SMILES:O=C(C=1C=NC=CC1)N(CC)CC
- Synonyms:
- Anacardone
- Astrocar
- Inicardio
- Kardiamid
- Leptamin
- Mediamid
- Niamine
- Nicamide
- Nicetamide
- Nicethamid
- See more synonyms
- Nicor
- Nicotinic Acid Diethyl Amide
- Nikethamide
- Nikotin
- N,N-diethyl-3-pyridinecarboxamide
- N,N-Diethylnicotinamide
- Percoral
- Procardine
- Pyridine-3-Carboxyldiethylamide
- Pyridine-3-Carboxylic Acid Diethylamide
- Reformin
- Salvacord
- Stellamine
- Stimulin
- Vasozol
- Diethyl-Nicotamide
- Dietilamide-Carbopiridina
- Dinacoryl
- Betapyrimidum
- Camphozone
- Cardiamid
- Cardiamine
- Cardamine
- Citocor
- Coracon
- Coraethamidum
- Coramine
- Corazone
- Cordiamin
- Cordynil
- Corediol
- Coretone
- Cormid
- Cornotone
- Corvitan
- Corvotone
- Danamine
- Elitone
- Hansacor
- N,N-diethylpyridine-3-carboxamide
- 3-(N,N-Diethylcarbamoyl)pyridine
- 3-Pyridinecarboxamide, N,N-diethyl-
- Anacordone
- Canfodiamina
- Carbamidal
- Cardiamide
- Cardimon
- Coractiv N
- Coramine (pharmaceutical)
- Cordiamine
- Cormed
- Cormotyl
- Corvin
- Corvitol
- Diethylnicotinamide
- Dynacoryl
- Ecoran
- Eucoran
- Kordiamin
- Nicetamida
- Nicethamide
- Ni-Cor
- Nicorine
- Nicotinamide, N,N-diethyl-
- Nicotinic acid diethylamide
- Nikardin
- Niketamide
- Niketamine
- Nikethamid
- Niketharol
- Nikethyl
- Nikorin
- Niquetamide
- Nsc 130820
- Nsc 169863
- Nsc 62103
- Pyricardyl
- Pyridine-3-carboxydiethylamide
- Rehormin
- Salvacard
- Sancora
- Solyacord
- Ventramine

N,N-Diethylnicotinamide
Ref: 3B-D0514
25g | 36.00 € | ||
500g | 282.00 € |

Nikethamide CRS
Ref: 41-N0800000
1ml | 115.00 € |

Nikethamide
Ref: TM-T0048
1g | 55.00 € | ||
5g | 111.00 € | ||
10g | 163.00 € | ||
500mg | 48.00 € | ||
1mL*10mM (DMSO) | 35.00 € |

Nikethamide
Ref: 7W-GP1304
25g | 33.00 € | ||
100g | 69.00 € | ||
250g | 128.00 € | ||
500g | 213.00 € |

Nikethamide, EP grade
Ref: 7W-GP1011
Undefined size | To inquire |

N,N-Diethylnicotinamide, 97%
Ref: AC-11447
25g | 37.00 € | ||
100g | 115.00 € |

Nikethamide
Controlled ProductRef: 86-MM0627.00
500mg | 303.00 € |

Ref: 4Z-N-133029
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |

N,N-Diethylnicotinamide (Nikethamide)
Ref: TR-N460000
10g | 291.00 € | ||
25g | 345.00 € | ||
2500mg | 252.00 € |

N,N-Diethylnicotinamide
Controlled ProductRef: 3D-FD31942
25g | 147.00 € |