CAS 59-31-4

2-Hydroxyquinoline

Description:

2-Hydroxyquinoline, with the CAS number 59-31-4, is an organic compound characterized by a quinoline structure with a hydroxyl group (-OH) positioned at the second carbon. This compound appears as a pale yellow to white crystalline solid and is known for its aromatic properties. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water. 2-Hydroxyquinoline exhibits various chemical properties, including the ability to form chelates with metal ions, making it useful in coordination chemistry and as a ligand in various applications. Additionally, it has been studied for its potential biological activities, including antimicrobial and anticancer properties. The compound can undergo typical reactions of phenolic compounds, such as oxidation and substitution. Its derivatives are also of interest in the development of pharmaceuticals and agrochemicals. Safety precautions should be taken when handling this compound, as it may pose health risks upon exposure.

Formula: C₉H₇NO

InChI: InChI=1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)

InChI key: InChIKey=LISFMEBWQUVKPJ-UHFFFAOYSA-N

SMILES: O=C1NC=2C(C=C1)=CC=CC2

Synonyms:

• 1,2-Dihydro-2-oxoquinoline
• 1H-Quinolin-2-one
• 2(1H)-Quinolone
• 2-Hydroxyquinoline
• 2-Oxo-1,2-dihydroquinoline
• 2-Quinolinol
• 2-Quinolinone
• 2-Quinolone
• Carbostyril
• NSC 156783
• NSC 554
• NSC 97217
• Quinolin-2-ol
• o-Aminocinnamic acid lactam
• quinolin-2(1H)-one
• α-Hydroxyquinoline
• α-Quinolone

2-Quinolinol

CAS: 59-31-4

Formula: C₉H₇NO

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 145.16

Ref: 3B-H0304

2-Hydroxyquinoline

CAS: 59-31-4

Compound PDK0291, with CAS No. 59-31-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0291 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Formula: C₉H₇NO

Color and Shape: White Solid

Molecular weight: 145.15

Ref: TM-PDK0291

2-Hydroxyquinoline (2-Quinolinol)

CAS: 59-31-4

Formula: C₉H₇NO

Molecular weight: 145.16

Ref: 7W-GK3524

2-Hydroxyquinoline

CAS: 59-31-4

2-Hydroxyquinoline

Formula: C₉H₇NO

Purity: 96%

Color and Shape: faint brown solid

Molecular weight: 145.16g/mol

Ref: 54-OR18280

Quinolin-2(1H)-one

CAS: 59-31-4

Formula: C₉H₇NO

Purity: 97%

Color and Shape: Solid

Molecular weight: 145.161

Ref: 10-F358402

2-Hydroxyquinoline

CAS: 59-31-4

2-Hydroxyquinoline is a coumarin derivative that has inhibitory properties against a variety of human pathogens, including the causative agent of malaria. It binds to the active site of the enzyme xanthine oxidase, which catalyzes the oxidation of hypoxanthine to xanthine and then to uric acid. 2-Hydroxyquinoline inhibits this reaction, preventing the accumulation of uric acid in the blood and urine. This compound also has potential anticancer activity due to its ability to inhibit tumor cell proliferation in human prostate cancer cells. 2-Hydroxyquinoline is metabolized by cytochrome P450 enzymes and has pharmacokinetic properties that include an inhibitory dose (ID50) of 1mg/kg.

Formula: C₉H₇NO

Purity: Min. 95%

Color and Shape: White To Light (Or Pale) Yellow To Light (Or Pale) Green To Purple Brown Solid

Molecular weight: 145.16 g/mol

Ref: 3D-FH40553