CAS 59-33-6

Pyrilamine maleate

Description:

Pyrilamine maleate is an antihistamine compound primarily used to alleviate allergic reactions and symptoms such as hay fever and urticaria. It is classified as a first-generation antihistamine, which means it can cross the blood-brain barrier, often leading to sedative effects. The chemical structure of pyrilamine maleate consists of a pyridine ring and an amine group, contributing to its pharmacological activity by blocking histamine H1 receptors. The maleate salt form enhances its solubility and stability. Pyrilamine maleate is typically administered orally and is available in various formulations, including tablets and syrups. Common side effects may include drowsiness, dry mouth, and dizziness, which are characteristic of many first-generation antihistamines. It is important to use this medication under medical supervision, especially in individuals with pre-existing conditions or those taking other medications, due to potential interactions and contraindications. Overall, pyrilamine maleate serves as an effective option for managing allergic symptoms, though caution is advised regarding its sedative properties.

Formula: C₂₁H₂₇N₃O₅

InChI: InChI=1/C17H23N3O.C4H4O4/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15;5-3(6)1-2-4(7)8/h4-11H,12-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/p-2/b;2-1-

InChI key: InChIKey=JXYWFNAQESKDNC-BTJKTKAUSA-N

SMILES: C(=C\C(O)=O)\C(O)=O.N(CC1=CC=C(OC)C=C1)(CCN(C)C)C2=CC=CC=N2

Synonyms:

• 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-, (2Z)-2-butenedioate (1:1)
• 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-, (Z)-2-butenedioate (1:1)
• 1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-, (2Z)-2-butenedioate (1:1)
• 1,2-Ethanediamine, N¹-[(4-methoxyphenyl)methyl]-N²,N²-dimethyl-N¹-2-pyridinyl-, (2Z)-2-butenedioate (1:1)
• 2-[(2-Dimethylaminoethyl)(p-methoxybenzyl)amino]-pyridine maleate
• 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine Bimaleate
• AH
• Anisopyradamine
• Antamine
• Anthisan maleate
• Antihist
• Antisan
• Diaminide maleate
• Enrumay
• Histalet Forte
• Histalon
• Histan
• Histapyran
• Histatex
• Histavet P
• Maleate De Mepyramine
• Maleato De Mepiramina
• Maleinsaeure-(2-(N-(2-Dimethylamino-Aethyl)-N-(P-Methoxy-Benzyl)-Amino)-Pyridin) - Salz
• Mepyramine hydrogen maleinate
• Mepyramine maleate
• Mepyraminmaleat
• Minihist
• N-(4-methoxybenzyl)-N',N'-dimethyl-N-(pyridin-2-yl)ethane-1,2-diamine
• N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine (2E)-but-2-enedioate
• N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine (2Z)-but-2-enedioate
• N-p-Methoxybenzyl-N',N'-dimethyl-N-α-pyridylethylenediamine maleate
• Neo-Antergan maleate
• Neoantergan maleate
• Nsc 3604
• Paramal
• Paraminyl
• Paraminyl maleate
• Parmal
• Prefrin A
• Pymafed
• Pyra Maleate
• Pyramal
• Pyranilamine maleate
• Pyraninyl
• Pyranisamine maleate
• Pyridine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]-, maleate (1:1)
• Pyrilamine Maleate
• Renstamin
• Stamine
• Stangen
• Stangen maleate
• Statomin maleate
• Thylogen
• Thylogen maleate
• N-[4-METHOXY-PHENYL]METHYL-N',N'-DIMETHYL-N[2-PYRIDINYL]-1,2-ETHANEDIAMINE MALEATE SALT
• diaminidemaleate
• MEPYRAMINE MALEATE SALT
• 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-pyridinmaleate(1:1)
• (z)-2-butenedioat
• n-((4-methoxyphenyl)methyl)-n,n’-dimethyl-n-2-pyridinyl-2-ethanediamine
• PYRILAMINE MALEATE SALT
• anthisanmaleate
• 2-ethanediamine,n-[(4-methoxyphenyl)methyl]-n’,n’-dimethyl-n-2-pyridinyl-(
• 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)pyridinebimaleate
• N-(P-METHOXYBENZYL)-N',N'-DIMETHYL-N-2-PYRIDYLETHYLENEDIAMINE MALEATE

Pyrilamine Maleate

CAS: 59-33-6, 91-84-9

Formula: C₁₇H₂₃N₃O·C₄H₄O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 401.46

Ref: 3B-P2369

Pyrilamine maleate

CAS: 59-33-6

Selective inverse agonist for the H-1 histamine receptor

Formula: C₁₇H₂₃N₃O·C₄H₄O₄

Molecular weight: 401.46

Ref: 02-J63247

Mepyramine Maleate

CAS: 59-33-6

Color and Shape: Neat

Ref: 61-FOR0559.00

MEPYRAMINE MALEATE CRS

CAS: 59-33-6

MEPYRAMINE MALEATE CRS

Ref: 41-M0500000

Pyrilamine Maleate

CAS: 59-33-6

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₇H₂₃N₃O·C₄H₄O₄

Color and Shape: Powder

Molecular weight: 401.47

Ref: 45-1588004

1,2-Ethanediamine,N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-,(2Z)-2-butenedioate (1:1)

CAS: 59-33-6

Formula: C₂₁H₂₇N₃O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 401.4562

Ref: IN-DA00IAHB

Mepyramine maleate

CAS: 59-33-6

Mepyramine maleate is a mild hypnotic, local anesthetic, and H1 histamine antagonist for allergies and colds.

Formula: C₂₁H₂₇N₃O₅

Purity: 99.51% - 99.7%

Color and Shape: White Crystalline Powder

Molecular weight: 401.47

Ref: TM-T1232

Mepyramine Maleate

CAS: 59-33-6

Formula: C₁₇H₂₃N₃O·C₄H₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 285.39 116.07

Ref: 4Z-M-179001

Mepyramine maleate

CAS: 59-33-6

Mepyramine maleate

Purity: ≥98%

Molecular weight: 401.47g/mol

Ref: 54-BUP18353

Pyrilamine maleate salt

CAS: 59-33-6

Formula: C₁₇H₂₃N₃O·C₄H₄O₄

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 401.46

Ref: 7W-GP6304

N1-(4-Methoxybenzyl)-N2,N2-Dimethyl-N1-(Pyridin-2-Yl)Ethane-1,2-Diamine Maleate

CAS: 59-33-6

N1-(4-Methoxybenzyl)-N2,N2-Dimethyl-N1-(Pyridin-2-Yl)Ethane-1,2-Diamine Maleate

Purity: 98%

Molecular weight: 401.46g/mol

Ref: 54-OR1030388

Mepyramine maleate

Controlled Product

CAS: 59-33-6

Formula: C₁₇H₂₃N₃O·C₄H₄O₄

Color and Shape: Neat

Molecular weight: 401.46

Ref: 04-C14896000

Mepyramine Maleate

Controlled Product

CAS: 59-33-6

Formula: C₁₇H₂₃N₃O·C₄H₄O₄

Color and Shape: Neat

Molecular weight: 401.46

Ref: 86-MM0559.00

Pyrilamine Maleate Salt

Controlled Product

CAS: 59-33-6

Applications Antihistaminic.
References Watanabe, T., et al.: Brain Res., 295, 13 (1984), Nakazato, E., et al.: Life Sci., 67, 1139 (2000), Masuoka, T., et al.: Brain Res. Bull., 73, 231 (2007),

Formula: C₁₇H₂₃N₃O·C₄H₄O₄

Color and Shape: White

Molecular weight: 401.46

Ref: TR-P997225

Pyrilamine maleate

CAS: 59-33-6

Pyrilamine maleate salt is a reagent used for optical rotation measurements. It is also known to be an antihistamine that has been shown to have mutagenic effects on Salmonella typhimurium and other bacteria. Pyrilamine maleate salt inhibits potassium ion transport across the cell membrane, which can lead to hyperpolarization of the cell membrane and inhibition of the uptake of sodium ions. This inhibition leads to an increase in intracellular sodium concentrations, which in turn leads to decreased ATP production.

Formula: C₁₇H₂₃N₃O•C₄H₄O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 401.46 g/mol

Ref: 3D-FP27345

Pyrilamine-D6 Maleate Salt

Controlled Product

CAS: 59-33-6

Formula: C₁₇H₁₇D₆N₃O•C₄H₄O₄

Color and Shape: Neat

Molecular weight: 407.5

Ref: TR-P997236