CAS 59-33-6: Pyrilamine maleate
Description:Pyrilamine maleate is an antihistamine compound primarily used to alleviate allergic reactions and symptoms such as hay fever and urticaria. It is classified as a first-generation antihistamine, which means it can cross the blood-brain barrier, often leading to sedative effects. The chemical structure of pyrilamine maleate consists of a pyridine ring and an amine group, contributing to its pharmacological activity by blocking histamine H1 receptors. The maleate salt form enhances its solubility and stability. Pyrilamine maleate is typically administered orally and is available in various formulations, including tablets and syrups. Common side effects may include drowsiness, dry mouth, and dizziness, which are characteristic of many first-generation antihistamines. It is important to use this medication under medical supervision, especially in individuals with pre-existing conditions or those taking other medications, due to potential interactions and contraindications. Overall, pyrilamine maleate serves as an effective option for managing allergic symptoms, though caution is advised regarding its sedative properties.
Formula:C17H23N3O·C4H4O4
InChI:InChI=1S/C17H23N3O.C4H4O4/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15;5-3(6)1-2-4(7)8/h4-11H,12-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key:InChIKey=JXYWFNAQESKDNC-BTJKTKAUSA-N
SMILES:O=C(O)C=CC(=O)O.N=1C=CC=CC1N(CC2=CC=C(OC)C=C2)CCN(C)C
- Synonyms:
- 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-, (2Z)-2-butenedioate (1:1)
- 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-, (Z)-2-butenedioate (1:1)
- 1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-, (2Z)-2-butenedioate (1:1)
- 1,2-Ethanediamine, N<sup>1</sup>-[(4-methoxyphenyl)methyl]-N<sup>2</sup>,N<sup>2</sup>-dimethyl-N<sup>1</sup>-2-pyridinyl-, (2Z)-2-butenedioate (1:1)
- 2-[(2-Dimethylaminoethyl)(p-methoxybenzyl)amino]-pyridine maleate
- 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine Bimaleate
- AH
- Anisopyradamine
- Antamine
- Anthisan maleate
- See more synonyms
- Antihist
- Antisan
- Diaminide maleate
- Enrumay
- Histalet Forte
- Histalon
- Histan
- Histapyran
- Histatex
- Histavet P
- Maleate De Mepyramine
- Maleato De Mepiramina
- Maleinsaeure-(2-(N-(2-Dimethylamino-Aethyl)-N-(P-Methoxy-Benzyl)-Amino)-Pyridin) - Salz
- Mepyramine hydrogen maleinate
- Mepyramine maleate
- Mepyraminmaleat
- Minihist
- N-(4-methoxybenzyl)-N',N'-dimethyl-N-(pyridin-2-yl)ethane-1,2-diamine
- N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine (2E)-but-2-enedioate
- N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine (2Z)-but-2-enedioate
- N-p-Methoxybenzyl-N',N'-dimethyl-N-α-pyridylethylenediamine maleate
- Neo-Antergan maleate
- Neoantergan maleate
- Nsc 3604
- Paramal
- Paraminyl
- Paraminyl maleate
- Parmal
- Prefrin A
- Pymafed
- Pyra Maleate
- Pyramal
- Pyranilamine maleate
- Pyraninyl
- Pyranisamine maleate
- Pyridine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]-, maleate (1:1)
- Pyrilamine Maleate
- Renstamin
- Stamine
- Stangen
- Stangen maleate
- Statomin maleate
- Thylogen
- Thylogen maleate