CAS 59-66-5

Acetazolamide

Description:

Acetazolamide is a carbonic anhydrase inhibitor primarily used as a diuretic and in the treatment of glaucoma, altitude sickness, and certain types of epilepsy. Its chemical formula is C4H6N4O3S, and it features a sulfonamide group, which is integral to its mechanism of action. Acetazolamide works by inhibiting the enzyme carbonic anhydrase, leading to decreased bicarbonate reabsorption in the kidneys, resulting in increased urine output and a reduction in intraocular pressure. The substance is typically administered orally and is known for its relatively rapid onset of action. Acetazolamide is generally well-tolerated, but potential side effects may include metabolic acidosis, electrolyte imbalances, and allergic reactions. It is contraindicated in patients with a known hypersensitivity to sulfonamides. The compound is classified as a prescription medication and should be used under medical supervision, particularly in individuals with pre-existing health conditions. Its efficacy and safety profile make it a valuable option in specific therapeutic contexts.

Formula: C₄H₆N₄O₃S₂

InChI: InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)

InChI key: InChIKey=BZKPWHYZMXOIDC-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C=1SC(NC(C)=O)=NN1

Synonyms:

• 2-Acetamido-1,3,4-thiadiazole-5-sulfonamide
• 2-Acetamido-5-Sulfamoyl-1,3,4-Thiadiazole
• 2-Acetamido-5-sulfonamido-1,3,4-thiadiazole
• 2-Acetylamino-1,3,4-Thiadiazole-5-Sulfonamide
• 5-Acetamide-1,3,4-thiadiazole-2-sulfonamide
• 5-Acetamido-1,3,4-Thiadiazole-2-Sulfonamide
• 5-Acetamido-1,3,4-thiodiazole-2-sulfonamide
• 5-Acetylamino-1,3,4-thiadiazol-2-ylsulfonamide
• Acetamide, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-
• Acetamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-
• Acetamox
• Acetazolamid
• Acetazolamida
• Atenezol
• Carbonic anhydrase inhibitor 6063
• Cidamex
• Defiltran
• Dehydratin
• Diacarb
• Diakarb
• Diamox
• Didoc
• Diluran
• Diuramid
• Diuramide
• Diureticum-Holzinger
• Diuriwas
• Diutazol
• Donmox
• Edemox
• Eumicton
• Fonurit
• Glaupax
• Glupax
• L 579486
• N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
• N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide
• Natrionex
• Nephramid
• Nephramide
• Nsc 145177

Acetazolamide

CAS: 59-66-5

Formula: C₄H₆N₄O₃S₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 222.24

Ref: 3B-A2598

Acetazolamide, 99%

CAS: 59-66-5

Acetazolamide acts as a carbonic anhydrase inhibitor which increases cerebral blood flow. It inhibits water permeability of membranes by interacting with aquaporins. It is used for the medical treatment of glaucoma, epileptic seizure, idiopathic intracranial hypertension, altitude sickness, cystinur

Formula: C₄H₆N₄O₃S₂

Purity: 99%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 222.25

Ref: 02-L07562

ACETAZOLAMIDE CRS

CAS: 59-66-5

ACETAZOLAMIDE CRS

Formula: C₄H₆N₄O₃S₂

Color and Shape: Powder.

Molecular weight: 222.2454

Ref: 41-A0100000

ACETAZOLAMIDE FOR SYSTEM SUITABILITY CRS

CAS: 59-66-5

ACETAZOLAMIDE FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001084

ACETAZOLAMIDE RS

CAS: 59-66-5

ACETAZOLAMIDE RS

Formula: C₄H₆N₄O₃S₂

Molecular weight: 222.2454

Ref: 41-ICRS0202

Acetazolamide

CAS: 59-66-5

Acetazolamide

Formula: C₄H₆N₄O₃S₂

Purity: 99.8%

Color and Shape: Off-White

Molecular weight: 221.98813

Ref: 47-904

Acetazolamide

CAS: 59-66-5

Sulfonamides used as drugs

Formula: C₄H₆N₄O₃S₂

Color and Shape: White Pale Yellow Crystalline Powder

Molecular weight: 222.25

Ref: 45-1005004

Acetazolamide

CAS: 59-66-5

Formula: C₄H₆N₄O₃S₂

Purity: ≥ 97.0%

Color and Shape: White to off-white powder

Molecular weight: 222.25

Ref: 7W-GP7201

Acetazolamide

CAS: 59-66-5

Acetazolamide (Diamox) is a Carbonic Anhydrase Inhibitor. The mechanism of action of acetazolamide is as a Carbonic Anhydrase Inhibitor. The chemical classification of acetazolamide is Sulfonamides.

Formula: C₄H₆N₄O₃S₂

Purity: 99.61% - 99.94%

Color and Shape: Crystals From Water 1992)

Molecular weight: 222.25

Ref: TM-T0813

Acetazolamide-13C2-d3

CAS: 59-66-5

Formula: C₂₁₃C₂H₃D₃N₄O₃S₂

Molecular weight: 227.24

Ref: 4Z-A-353

Acetazolamide

CAS: 59-66-5

Acetazolamide

Purity: ≥95%

Molecular weight: 222.249g/mol

Ref: 54-OR1022567

Acetazolamide

CAS: 59-66-5

Formula: C₄H₆N₄O₃S₂

Color and Shape: White To Off-White Solid

Molecular weight: 222.24

Ref: 4Z-A-351

Acetazolamide

Controlled Product

CAS: 59-66-5

Formula: C₄H₆N₄O₃S₂

Color and Shape: Neat

Molecular weight: 222.25

Ref: 86-MM0648.00

Acetazolamide

CAS: 59-66-5

Formula: C₄H₆N₄O₃S₂

Color and Shape: Neat

Molecular weight: 222.25

Ref: 04-C10017800

Phoxim 1000 µg/mL in Acetone

Controlled Product

CAS: 59-66-5

Stability Hygroscopic
Applications Carbonic anhydrase inhibitor. Diuretic.
References Vitale, R., et al.: J. Med. Chem., 52, 5990 (2009), Bell, H., et al.: Am. J. Physiol., 297, R370 (2009), Maresca, A., et al.: Bioorg. Med. Chem. Lett., 19, 4929 (2009), Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009),

Formula: C₄H₆N₄O₃S₂

Color and Shape: Off-White

Molecular weight: 222.25

Ref: TR-A161500

Acetazolamide

CAS: 59-66-5

Color and Shape: Neat

Ref: 61-FOR0648.00

Acetazolamide

CAS: 59-66-5

Formula: C₄H₆N₄O₃S₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 222.2454

Ref: IN-DA003NMH

Acetazolamide

Controlled Product

CAS: 59-66-5

Inhibits carbonic anhydrase; diuretic

Formula: C₄H₆N₄O₃S₂

Purity: 98.00 To 102.00%

Color and Shape: White Powder

Molecular weight: 222.25 g/mol

Ref: 3D-FA16948