CAS 59-66-5: Acetazolamide
Description:Acetazolamide is a carbonic anhydrase inhibitor primarily used as a diuretic and in the treatment of glaucoma, altitude sickness, and certain types of epilepsy. Its chemical formula is C4H6N4O3S, and it features a sulfonamide group, which is integral to its mechanism of action. Acetazolamide works by inhibiting the enzyme carbonic anhydrase, leading to decreased bicarbonate reabsorption in the kidneys, resulting in increased urine output and a reduction in intraocular pressure. The substance is typically administered orally and is known for its relatively rapid onset of action. Acetazolamide is generally well-tolerated, but potential side effects may include metabolic acidosis, electrolyte imbalances, and allergic reactions. It is contraindicated in patients with a known hypersensitivity to sulfonamides. The compound is classified as a prescription medication and should be used under medical supervision, particularly in individuals with pre-existing health conditions. Its efficacy and safety profile make it a valuable option in specific therapeutic contexts.
Formula:C4H6N4O3S2
InChI:InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
InChI key:InChIKey=BZKPWHYZMXOIDC-UHFFFAOYSA-N
SMILES:O=C(NC1=NN=C(S1)S(=O)(=O)N)C
- Synonyms:
- 2-Acetamido-1,3,4-thiadiazole-5-sulfonamide
- 2-Acetamido-5-Sulfamoyl-1,3,4-Thiadiazole
- 2-Acetamido-5-sulfonamido-1,3,4-thiadiazole
- 2-Acetylamino-1,3,4-Thiadiazole-5-Sulfonamide
- 5-Acetamide-1,3,4-thiadiazole-2-sulfonamide
- 5-Acetamido-1,3,4-Thiadiazole-2-Sulfonamide
- 5-Acetamido-1,3,4-thiodiazole-2-sulfonamide
- 5-Acetylamino-1,3,4-thiadiazol-2-ylsulfonamide
- Acetamide, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-
- Acetamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-
- See more synonyms
- Acetamox
- Acetazolamid
- Acetazolamida
- Atenezol
- Carbonic anhydrase inhibitor 6063
- Cidamex
- Defiltran
- Dehydratin
- Diacarb
- Diakarb
- Diamox
- Didoc
- Diluran
- Diuramid
- Diuramide
- Diureticum-Holzinger
- Diuriwas
- Diutazol
- Donmox
- Edemox
- Eumicton
- Fonurit
- Glaupax
- Glupax
- L 579486
- N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
- N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide
- Natrionex
- Nephramid
- Nephramide
- Nsc 145177
- Phonurit
