CAS 59-67-6

Nicotinic acid

Description:

Nicotinic acid, also known as niacin or vitamin B3, is an organic compound with the molecular formula C6H5NO2. It is a water-soluble vitamin that plays a crucial role in cellular metabolism, particularly in the conversion of carbohydrates, fats, and proteins into energy. Nicotinic acid is characterized by its white crystalline appearance and a slightly bitter taste. It is soluble in water and alcohol but insoluble in non-polar solvents. The compound exhibits a pKa value around 4.75, indicating its acidic nature. Nicotinic acid is essential for the synthesis of coenzymes NAD and NADP, which are vital for redox reactions in biological systems. Additionally, it has therapeutic applications, including the treatment of dyslipidemia, as it can help lower cholesterol levels and improve cardiovascular health. However, excessive intake can lead to side effects such as flushing, gastrointestinal distress, and liver toxicity. Overall, nicotinic acid is a significant nutrient with diverse biological functions and health benefits.

Formula: C₆H₅NO₂

InChI: InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key: InChIKey=PVNIIMVLHYAWGP-UHFFFAOYSA-N

SMILES: C(O)(=O)C=1C=CC=NC1

Synonyms:

• 3-Carboxylpyridine
• 3-Carboxypyridine
• 3-Pyridylcarboxylic acid
• Acide nicotinique
• Acido Nicotinico
• Akotin
• Apelagrin
• Bovi-Niacin
• CaRo 03
• Daskil
• Disperse NNO
• E 375
• Efacin
• Enduracin
• Linic
• Microvit B₃ Promix Niacin
• NiaShure
• Niac
• Niacin
• Niacor
• Niaspan
• Nicacid
• Nicangin
• Nico-Span
• Nicobid
• Nicodelmine
• Nicolar
• Niconacid
• Nicosan 3
• Nicotinic Acid
• Nicotinipca
• Nicotinsaeure
• Nicotinsaure
• Nicyl
• Nsc 169454
• Nyclin
• Pellagrin
• Pelonin
• Pyridine-3-carboxylic acid
• Slo-niacin
• Sr 4390
• Vitamin B5
• Vitamin B₃
• Vitamin B₃ (niacin)
• Vitamin B₃ (nicotinic acid)
• Wampocap
• β-Pyridinecarboxylic acid
• TIMTEC-BB SBB004279123.11
• pyridine-3-carboxylate
• Pyridine -3-Carloxylic acid
• Beta-Picolinic Acid
• 3-Carboxy Pyridine
• 3-Picolinic Acid
• RARECHEM AL BO 0217
• AKOS BBS-00003719
• Acidum-Nicotinicum

Nicotinic acid 10 µg/mL in Acetonitrile

CAS: 59-67-6

Formula: C₆H₅NO₂

Color and Shape: Single Solution

Molecular weight: 123.11

Ref: 04-A15521000AL-10

Nicotinic acid

CAS: 59-67-6

Formula: C₆H₅NO₂

Color and Shape: White

Molecular weight: 123.11

Ref: 04-C15521000

Nicotinic Acid RS

CAS: 59-67-6

Color and Shape: White

Ref: 2K-1102000021

Nicotinic Acid

CAS: 59-67-6

Applications Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver , fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term “niacin” has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor).
References Darby, W.J., et al.: Nutr. Rev., 33, 289 (1975), Black, A., et al.: Eur. J. Clin. Nutr., 54, 395 (2000), Cole, T., et al.: Br. Med. J., 320, 1240 (2000), Forshee, R., et al.: J. Nutr., 134, 2733 (2004),

Formula: C₆H₅NO₂

Color and Shape: Neat

Molecular weight: 123.11

Ref: TR-N429250

Niacin

CAS: 59-67-6

Niacin, also known as nicotinic acid or vitamin B3, is a water-soluble vitamin that is necessary for the proper metabolism of fat and carbohydrates. Niacin lowers low-density lipoprotein cholesterol (LDL-C) levels by reducing the production of apolipoprotein B by the liver. This effect has been shown in both human and animal models. It is also important for maintaining healthy skin, eyes, and nerves. Niacin has been shown to be effective in treating bowel diseases such as Crohn's disease and ulcerative colitis. In addition to its lipid-lowering effects, it can also improve the function of mitochondria in cells.

Formula: C₆H₅NO₂

Purity: (Titration) 99.5 ~ 101.5%

Color and Shape: White Powder

Molecular weight: 123.11 g/mol

Ref: 3D-FN16182

Nicotinic Acid (Pyridine-3-Carboxylic Acid) for cell culture, 99%, Endotoxin (BET) 0.05EU/mg

CAS: 59-67-6

Formula: C₆H₅NO₂

Purity: min.99%

Color and Shape: White to off-white, Crystalline powder, Clear, Colourless to pale yellow

Molecular weight: 123.11

Ref: SR-50275

Nicotinic Acid (Pyridine-3-Carboxylic Acid) pure, 99%

CAS: 59-67-6

Formula: C₆H₅NO₂

Purity: min.99%

Color and Shape: White to off - white, Crystalline powder, Clear, Colourless to pale yellow

Molecular weight: 123.11

Ref: SR-86097

Nicotinamide EP Impurity A

CAS: 59-67-6

Formula: C₆H₅NO₂

Molecular weight: 123.11

Ref: ST-EA-CP-N35001

Nicotinic Acid

CAS: 59-67-6

Color and Shape: Neat

Ref: 61-FOR0553.00