CAS 59-85-8

4-(chloromercurio)benzoic acid

Description:

4-(Chloromercurio)benzoic acid, with the CAS number 59-85-8, is an organomercury compound characterized by the presence of a mercury atom bonded to a chlorinated benzene ring. This compound features a benzoic acid moiety, which includes a carboxylic acid functional group (-COOH) attached to a benzene ring. The chloromercury group introduces unique reactivity and properties, making it useful in various chemical applications, particularly in organic synthesis and as a reagent in biochemical studies. It is typically a white to pale yellow solid and is known for its potential toxicity due to the presence of mercury, necessitating careful handling and disposal. The compound is soluble in organic solvents but has limited solubility in water. Its reactivity can be attributed to the electrophilic nature of the mercury atom, allowing it to participate in nucleophilic substitution reactions. Due to its mercury content, it is important to consider environmental and health regulations when working with this substance.

Formula: C₇H₅ClHgO₂

InChI: InChI=1/C7H5O2.ClH.Hg/c8-7(9)6-4-2-1-3-5-6;;/h2-5H,(H,8,9);1H;/q;;+1/p-1/rC7H5HgO2.ClH/c8-6-3-1-5(2-4-6)7(9)10;/h1-4H,(H,9,10);1H/q+1;/p-1

InChI key: InChIKey=LWYLSZJDISINGV-UHFFFAOYSA-M

SMILES: C([O-])(=O)C=1C=C[C-]([Hg+2][Cl-])=CC1.[H+]

Synonyms:

• 4-Chloromercuriobenzoic Acid
• 4-Chloromercuribenzoic acid
• (4-Carboxyphenyl)(Chloro)Mercury
• (4-Carboxyphenyl)Mercury(1+) Chloride
• (4-Carboxyphenyl)chloromercury
• 4-(Chloromercuri)benzoic acid
• 4-Carboxyphenylmercuric chloride
• 4-Chlormercuriobenzoesaure
• Acide 4-chloromercuriobenzoique
• Acido 4-Cloromercuriobenzoico
• Benzoic Acid, 4-(Chloromercuric)-
• Mercurate(1-), (4-carboxylatophenyl)chloro-, hydrogen
• Mercury, (p-carboxyphenyl)chloro-
• Nsc 32866
• p-(Chloromercuri)benzoic acid
• p-Carboxyphenylmercuric chloride
• p-Chlormercuribenzoic acid
• p-Chloromercuric benzoic acid
• Pcmb
• (4-carboxylatophenyl)chloro-mercurate(1-hydrogen
• P-CHLOROMERCURIBENZOIC ACID, FREE ACID
• 4-(CHLOROMERCURI)BENZOIC ACID 95% (&
• usafd-3
• p-carboxyphenylmercuricchloride
• 4-carboxyphenylmercuricchloride
• P-CMB
• p-(chloromercuri)-benzoicaci
• 4-(HYDROXYMERCURI)BENZOIC ACID
• 4-(CHLOROMERCURIO)BENZOIC ACID
• 4-(HYDROXYMERCURIO)BENZOIC ACID
• p-chloro-mercuricbenzoicacid
• 4-(Chloromercuric)benzoic acid
• P-CHLOROMERCURIBENZOIC ACID
• P-CMBA
• (p-carboxyphenyl)chloro-mercur
• (p-Carboxyphenyl)chloromercury

4-Chloromercuribenzoic Acid

CAS: 59-85-8

Formula: C₇H₅ClHgO₂

Ref: TR-TRC-C367800

4-Chloromercuribenzoic Acid

Controlled Product

CAS: 59-85-8

Applications A useful sulfhydryl reagent that reacts with Histidine 225C, a residue of the NhaA-Na/H Antiporter of Escherichia Coli.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Olami, Y. et al.: J. Biol. Chem., 272, 3, 1761 (1997).

Formula: C₇H₅ClHgO₂

Color and Shape: White Crystalline Powder

Molecular weight: 357.16

Ref: TR-C367800

4-Chloromercuribenzoic acid

Controlled Product

CAS: 59-85-8

4-Chloromercuribenzoic acid (CMBA) is a toxic compound that is used as a preservative in cosmetics and pharmaceuticals. It inhibits the enzyme succinic dehydrogenase, which is involved in the Krebs cycle. CMBA also binds to proteins to form covalent bonds, which disrupts protein function. It has been shown to inhibit several enzymes including phosphofructokinase, hexokinase, and glutathione reductase. CMBA binds to metal ions such as copper or zinc by forming a chelate complex with them and this binding process reduces the availability of these metals for other cellular processes. CMBA also forms covalent bonds with receptor molecules such as histidine or cysteine residues on proteins. This binding process can lead to structural changes in the protein that result in inhibition of enzyme activity.

Formula: C₇H₅ClHgO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 357.16 g/mol

Ref: 3D-FC20247