CAS 59-87-0

Nitrofurazone

Description:

Nitrofurazone is an organic compound classified as a nitrofuran derivative, primarily known for its antimicrobial properties. It appears as a yellow to orange crystalline powder and is soluble in organic solvents but has limited solubility in water. The chemical formula of Nitrofurazone is C₇H₆N₄O₄, and it features a nitro group (-NO₂) attached to a furan ring, which contributes to its biological activity. Nitrofurazone is commonly used in veterinary medicine for the treatment of bacterial infections and is also employed in topical formulations for wound healing due to its ability to inhibit bacterial growth. Its mechanism of action involves the disruption of bacterial DNA and protein synthesis. While effective, Nitrofurazone can cause side effects, including skin irritation and allergic reactions in some individuals. Due to its potential toxicity and the development of resistance, its use is regulated in many countries, and it is important to follow guidelines for safe application.

Formula: C₆H₆N₄O₄

InChI: InChI=1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)

InChI key: InChIKey=IAIWVQXQOWNYOU-UHFFFAOYSA-N

SMILES: N(=O)(=O)C=1OC(C=NNC(N)=O)=CC1

Synonyms:

• (5-Nitro-2-furfurylidenamino)urea
• 1-(5-Nitro-2-furfurylidene)semicarbazide
• 2-Furaldehyde, 5-nitro-, semicarbazone
• 2-Furancarboxaldehyde, 5-nitro-, semicarbazone
• 2-Nitrofuran
• 2-[(5-Nitro-2-Furanyl)Methylene]-Hydrazinecarboxamide
• 5-Nitro-2-Furaldehyd-Semicarbazon
• 5-Nitro-2-furaldehyde semicarbazone
• 5-Nitro-2-furfural semicarbazone
• 5-Nitro-2-furfuraldehyde semicarbazone
• 5-Nitrofuran-2-Carbaldehyde Semicarbazone
• 5-Nitrofurazone
• 5-Nitrofurfural semicarbazone
• Aldomycin
• Alfucin
• Amifur
• Babrocid
• Chemofuran
• Coxistat
• Fura-Septin
• FuraZin
• Furacilin
• Furacilinum
• Furacin
• Furacin Ointment
• Furacine
• Furacinetten
• Furacoccid
• Furacycline
• Furalcyn
• Furaldon
• Furaplast
• Furaseen
• Furaskin
• Furaziline
• Furazol W
• Furesol
• Hydrazinecarboxamide, 2-[(5-nitro-2-furanyl)methylene]-
• Mammex
• Mastofuran
• Monafuracin
• NFS
• Nefco
• Nfz mix
• Nifucin
• Nifuzon
• Nitrofuraldehyde semicarbazone
• Nitrofuran
• Nitrofuran (bactericide)
• Nitrofurazone
• Nitrophtharazone
• Nitrozone
• Nsc 1602
• Nsc 2100
• Nsc 44009
• Otofural
• Semioxamazide, 1-(5-nitrofurfurylidene)-
• Topifuran
• Vabrocid
• Veterinary nitrofurazone

Nitrofurazone in Methanol

CAS: 59-87-0

Methanol

Ref: BE-BePure-GBW(E)086484-1000

Nitrofurazone

CAS: 59-87-0

2-((5-Nitrofuran-2-yl)methylene)hydrazinecarboxamide

Formula: C₆H₆N₄O₄

Purity: 98+%

Molecular weight: 198.14

Ref: IN-DG131645

Nitrofurazone

CAS: 59-87-0

Formula: C₆H₆N₄O₄

Purity: 97%

Molecular weight: 198.138

Ref: 10-F544119

Nitrofurazone

CAS: 59-87-0

Nitrofurazone is a synthetic antimicrobial agent that has been shown to be effective against a wide range of bacteria, fungi, and viruses. This drug has been studied using electrochemical impedance spectroscopy (EIS) on cells from rat brain tumors. The EIS study yielded the most promising results when used in combination with malignant brain tumor cells. It was also found that nitrofurazone is not toxic to wild-type strains of Escherichia coli and Saccharomyces cerevisiae, but is toxic to resistant mutants of these organisms. Nitrofurazone may react with nitrite ions in solution to form nitrosating agents that can result in the formation of DNA or protein adducts which can lead to cell death.
Nitrofurazone was tested for its toxicity on human serum at different concentrations and it was found that this drug does not have significant toxicity on human serum.

Formula: C₆H₆N₄O₄

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 198.14 g/mol

Ref: 3D-FN26308