CAS 5906-30-9

N-cyclopropyl-N~2~-[(2,4-difluorophenyl)carbamoyl]-N-[(1-methyl-1H-pyrrol-2-yl)methyl]-N~2~-propan-2-ylglycinamide

Description:

N-cyclopropyl-N~2~-[(2,4-difluorophenyl)carbamoyl]-N-[(1-methyl-1H-pyrrol-2-yl)methyl]-N~2~-propan-2-ylglycinamide, with CAS number 5906-30-9, is a synthetic organic compound characterized by its complex structure, which includes a cyclopropyl group, a difluorophenyl moiety, and a pyrrolidine derivative. This compound features multiple functional groups, including amides and glycine derivatives, which contribute to its potential biological activity. The presence of fluorine atoms typically enhances lipophilicity and metabolic stability, making such compounds of interest in medicinal chemistry. The cyclopropyl ring can impart unique steric and electronic properties, influencing the compound's interaction with biological targets. Additionally, the presence of the pyrrolidine ring may enhance binding affinity to specific receptors or enzymes. Overall, this compound's intricate structure suggests potential applications in pharmaceuticals, particularly in the development of novel therapeutic agents. However, detailed studies on its pharmacodynamics, pharmacokinetics, and safety profile would be necessary to fully understand its potential uses.

Formula: C₂₁H₂₆F₂N₄O₂

InChI: InChI=1/C21H26F2N4O2/c1-14(2)26(21(29)24-19-9-6-15(22)11-18(19)23)13-20(28)27(16-7-8-16)12-17-5-4-10-25(17)3/h4-6,9-11,14,16H,7-8,12-13H2,1-3H3,(H,24,29)

SMILES: CC(C)N(CC(=O)N(Cc1cccn1C)C1CC1)C(=Nc1ccc(cc1F)F)O

Synonyms:

• 1-Piperazinesulfonamide
• PIPERAZINE-1-SULFONAMIDE
• 1-piperazinesulfonamide(SALTDATA: FREE)
• 1-Piperazinesulfonamide(7CI,8CI,9CI)

Piperazine-1-sulfonamide

CAS: 5906-30-9

Piperazine-1-sulfonamide is a protein inhibitor that belongs to the group of regulatory agents. It is used to regulate the growth of various types of cells, including immune cells and smooth muscle cells. Piperazine-1-sulfonamide has been shown to inhibit chemokine receptor activity in inflammatory bowel disease, which may be due to its ability to inhibit CXCR4 and CCR5 receptors. This drug also inhibits dpp-iv, an enzyme involved in protein degradation. The pharmacokinetic properties of this agent are not well studied, but it does show toxicity studies in rats at higher doses. Piperazine-1-sulfonamide can cause congestive heart failure and liver damage at high doses, so it should not be used for prolonged periods of time.

Formula: C₄H₁₁N₃O₂S

Purity: Min. 95%

Molecular weight: 165.21 g/mol

Ref: 3D-FAA90630