CAS 59090-48-1

1-(2-deoxypentofuranosyl)-5-(triaza-1,2-dien-2-ium-1-ylmethyl)pyrimidine-2,4(1H,3H)-dione

Description:

1-(2-Deoxypentofuranosyl)-5-(triaza-1,2-dien-2-ium-1-ylmethyl)pyrimidine-2,4(1H,3H)-dione, with CAS number 59090-48-1, is a complex organic compound that features a pyrimidine core substituted with a deoxypentofuranosyl group and a triaza-1,2-dien-2-ium moiety. This compound is characterized by its unique structural components, which include a five-membered sugar ring and a nitrogen-rich heterocyclic system. The presence of the triaza group suggests potential for interesting reactivity and biological activity, possibly influencing nucleic acid interactions or serving as a pharmacophore in medicinal chemistry. The pyrimidine dione structure indicates that it may exhibit tautomeric forms, which can affect its chemical behavior and stability. Additionally, the compound may possess specific solubility characteristics and reactivity patterns due to its functional groups, making it of interest in both synthetic and biological chemistry contexts. Overall, this compound exemplifies the intricate relationship between structure and function in organic molecules, particularly in the realm of nucleoside analogs and their derivatives.

Formula: C₁₀H₁₄N₅O₅

InChI: InChI=1/C10H13N5O5/c11-14-12-2-5-3-15(10(19)13-9(5)18)8-1-6(17)7(4-16)20-8/h3,6-8,11,16-17H,1-2,4H2/p+1

5-(Azidomethyl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS: 59090-48-1

5-(Azidomethyl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Purity: 95%

Molecular weight: 283.24g/mol

Ref: 54-OR1053191

α-Azidothymidine

CAS: 59090-48-1

Nucleoside Derivatives - Azido-nucleosides, 5-Modified pyrimidine nucleosides

Formula: C₁₀H₁₃N₅O₅

Color and Shape: Solid

Molecular weight: 283.24

Ref: TM-TNU1111

5-(Azidomethyl)-2’-deoxyuridine

CAS: 59090-48-1

5-azidomethyl-2-deoxyuridine (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU (NE08701). Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.

Formula: C₁₀H₁₃N₅O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 283.24 g/mol

Ref: 3D-NA162993