CAS 59122-46-2
:Misoprostol
Description:
Misoprostol is a synthetic prostaglandin E1 analog, primarily used in medicine for its ability to induce uterine contractions and protect the gastric mucosa. It is characterized by its white to off-white crystalline powder form, which is soluble in water and organic solvents like ethanol. Misoprostol acts by binding to prostaglandin receptors, leading to various physiological effects, including the stimulation of uterine contractions, cervical ripening, and inhibition of gastric acid secretion. Its therapeutic applications include the prevention of gastric ulcers in patients taking nonsteroidal anti-inflammatory drugs (NSAIDs), as well as its use in obstetrics and gynecology for medical abortion and management of miscarriage. The compound is typically administered orally or vaginally, and its pharmacokinetics involve rapid absorption and metabolism, with a relatively short half-life. Misoprostol's safety profile is generally favorable, but it can cause side effects such as gastrointestinal disturbances and uterine hyperstimulation, necessitating careful monitoring during use.
Formula:C22H38O5
InChI:InChI=1/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3/b12-10+/t17-,18-,20-,22?/s2
InChI key:InChIKey=OJLOPKGSLYJEMD-YUQTXCCYNA-N
SMILES:C(=C/CC(CCCC)(C)O)\[C@@H]1[C@@H](CCCCCCC(OC)=O)C(=O)C[C@H]1O
Synonyms:- (+-)-Methyl (1R,2R,3R)-3-hydroxy-2-((E)-(4RS)-4-hydroxy-4-methyl-1-octenyl)-5-oxocyclopentaneheptanoate
- (11a,13E)-(±)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester
- (11alpha,13E)-(+)-11alpha,16-Dihydroxy-16-methyl-9-oxoprost-13E-en-1-oic acid methyl ester
- (±)-15-Deoxy-(16RS)-16-hydroxy-16-methyl-PGE1 Methyl Ester
- Cytotec
- Isprelor
- Misogon
- Misoprost
- Misoprostil
- Misotac
- Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (11α,13E)-
- Sc 29333
- methyl (11alpha,13E)-11-hydroxy-16,16-dimethyl-9-oxoprost-13-en-1-oate
- methyl (11alpha,13E,16S)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
- See more synonyms
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Found 13 products.
MISOPROSTOL FOR SYSTEM SUITABILITY CRS
CAS:MISOPROSTOL FOR SYSTEM SUITABILITY CRSFormula:C22H38O5Molecular weight:382.5341Misoprostol
CAS:Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analoguesFormula:C22H38O5Color and Shape:Colorless Light Yellow Liquid ViscousMolecular weight:382.27192Misoprostol
CAS:Misoprostol, a prostaglandin E1 derivative, has a strong inhibitory effect on gastric acid secretion, while having a contractile effect on pregnancy.Formula:C22H38O5Purity:99.78%Color and Shape:Water-Soluble Viscous LiquidMolecular weight:382.53Misoprostol (0.10% wt/v in METHYL ACETATE), min. 97%
CAS:Formula:C22H38O5Purity:min. 97%Color and Shape:White to Yellowish Oil (SOLUTION IN 10% METHYL ACETATE)Molecular weight:382.53Misoprostol (Mixture of Diastereomers)
CAS:Formula:C22H38O5Color and Shape:Pale Yellow OilMolecular weight:382.54Misoprostol
CAS:Formula:C22H38O5Purity:≥ 99.0%Color and Shape:Colourless to light yellow liquidMolecular weight:382.53Misoprostol
CAS:Controlled Product<p>Applications Misoprostol is a cytoprotective prostaglandin PGE1 analogue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Graham, Y., et al.: Lancet, 2, 1277 (1988); Graham, D.Y., et al.: Ann. Int. Med., 119, 257 (1993); Fletcher, H., et al.: Obstet. Gynecol., 83, 244 (1994);<br></p>Formula:C22H38O5Color and Shape:Light Yellow ViscousMolecular weight:382.53Misoprostol, 1% in cellulose
CAS:Controlled ProductFormula:C22H38O5Color and Shape:Single SolutionMolecular weight:382.53Misoprostol - 1% in cellulose
CAS:Controlled Product<p>Misoprostol is a nonsteroidal anti-inflammatory drug that is used for the treatment of dysmenorrhea and chronic non-specific low back pain. Misoprostol is also used in nephrology dialysis to decrease blood pressure, heart rate, and fluid retention in patients with congestive heart failure. It has been shown that misoprostol can be used to prevent preterm labor in pregnant women with a statistically significant reduction in the risk of miscarriage, preterm birth, and neonatal death. It has been shown that misoprostol can be administered orally or vaginally for the prevention of preterm labor. The pharmacokinetic properties of misoprostol are dose-dependent; higher doses result in faster absorption. Clinical relevance is dependent on the concentration-time curve, which determines how quickly the drug reaches its peak concentration. The clinical relevance of misoprostol is determined by the dose group (low dose or high dose), as well as diastolic</p>Formula:C22H38O5Purity:Min. 95%Color and Shape:PowderMolecular weight:382.53 g/molMisoprostol
CAS:Controlled Product<p>Misoprostol is a prostaglandin E1 analogue that is used for the prevention and treatment of peptic ulcers. It also has been shown to reduce the risk of gastric cancer in the general population, although this effect may be limited to patients with a history of nonsteroidal anti-inflammatory drug use. Misoprostol has been found to be more effective in women who have already given birth than in those who have not, with a statistically significant reduction in the incidence of pregnancy during long-term use. Misoprostol is metabolized by cytochrome P450 enzymes and excreted primarily through the kidneys. The drug's pharmacokinetic properties are dependent on diastolic blood pressure, body mass index, and levels of blood sampling. Intrauterine placement can also increase its efficacy as it bypasses first-pass metabolism.</p>Formula:C22H38O5Purity:Min. 95%Color and Shape:Colorless Clear LiquidMolecular weight:382.53 g/mol
