Z-Phe-Arg-pNA, also known as Z-Phenylalanine-Arginine-p-nitroanilide, is a synthetic peptide substrate commonly used in biochemical research, particularly in studies involving proteolytic enzymes. The "Z" in its name indicates that the phenylalanine residue is protected by a benzyloxycarbonyl (Z) group, which enhances the stability and solubility of the peptide. The presence of the arginine residue contributes to its specificity for certain enzymes, particularly those that cleave at basic amino acids. The p-nitroanilide (pNA) moiety serves as a chromogenic group, allowing for the quantification of enzymatic activity through colorimetric assays. Upon cleavage by specific proteases, the release of pNA results in a measurable color change, facilitating the study of enzyme kinetics and inhibition. Z-Phe-Arg-pNA is often utilized in laboratory settings to investigate the activity of serine proteases and other related enzymes, making it a valuable tool in both basic and applied biochemical research.

Z-Phe-Arg-pNA

59188-54-4: Z-Phe-Arg-pNA, also known as Z-Phenylalanine-Arginine-p-nitroanilide, is a synthetic peptide substrate commonly used in biochemical research, particularly in studies involving proteolytic enzymes. The "Z" in its name indicates that the phenylalanine residue is protected by a benzyloxycarbonyl (Z) group, which enhances the stability and solubility of the peptide. The presence of the arginine residue contributes to its specificity for certain enzymes, particularly those that cleave at basic amino acids. The p-nitroanilide (pNA) moiety serves as a chromogenic group, allowing for the quantification of enzymatic activity through colorimetric assays. Upon cleavage by specific proteases, the release of pNA results in a measurable color change, facilitating the study of enzyme kinetics and inhibition. Z-Phe-Arg-pNA is often utilized in laboratory settings to investigate the activity of serine proteases and other related enzymes, making it a valuable tool in both basic and applied biochemical research.

Z-FR-pNA, a sensitive chromogenic substrate for cathepsin L and papain. Z-FR-pNA is also cleaved by falcipain 2. CAS Number (net): 117761-01-0.

Z-Phe-Arg-pNA · HCl

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CAS 59188-54-4

Z-Phe-Arg-pNA

Z-Phe-Arg-pNA · HCl

Ref: 01-4009170

Z-Phe-Arg-pNA·HCl

Ref: 3D-FP110721