CAS 5922-60-1

2-Amino-5-chlorobenzonitrile

Description:

2-Amino-5-chlorobenzonitrile, with the CAS number 5922-60-1, is an organic compound characterized by the presence of an amino group (-NH2) and a cyano group (-C≡N) attached to a chlorinated benzene ring. This compound typically appears as a solid at room temperature and is soluble in polar solvents due to the presence of the amino group, which can engage in hydrogen bonding. The chlorine atom, located at the 5-position of the benzene ring, contributes to the compound's reactivity and influences its electronic properties. 2-Amino-5-chlorobenzonitrile is often utilized in organic synthesis and pharmaceutical research, serving as an intermediate in the production of various biologically active compounds. Its chemical structure allows for potential applications in agrochemicals and dyes as well. Safety precautions should be observed when handling this compound, as it may pose health risks if ingested or inhaled, and appropriate measures should be taken to mitigate exposure.

Formula: C₇H₅ClN₂

InChI: InChI=1S/C7H5ClN2/c8-6-1-2-7(10)5(3-6)4-9/h1-3H,10H2

InChI key: InChIKey=QYRDWARBHMCOAG-UHFFFAOYSA-N

SMILES: C(#N)C1=C(N)C=CC(Cl)=C1

Synonyms:

• 1-Cyano-2-amino-5-chlorobenzene
• 2-Amino-5-Chlorbenzoesaeurenitril
• 2-Amino-5-Chloro-Benzonitril
• 2-Amino-5-chlorobenzenecarbonitrile
• 2-Cyano-4-chloroaniline
• 4-Chloro-2-cyanoaniline
• 5-Chloro-2-aminobenzonitrile
• 5-Chloroanthranilonitrile
• 6-Amino-3-chlorobenzonitrile
• Acbn
• Amino(2-) 5-Chloro-Benzonitrile
• Anthranilonitrile, 5-chloro-
• Benzonitrile, 2-amino-5-chloro-
• Timtec-Bb Sbb004050

2-Amino-5-chlorobenzonitrile

CAS: 5922-60-1

Formula: C₇H₅ClN₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 152.58

Ref: 3B-A1572

2-Amino-5-chlorobenzonitrile, 97%

CAS: 5922-60-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₅ClN₂

Purity: 97%

Color and Shape: Pale yellow to cream, Powder

Molecular weight: 152.58

Ref: 02-B22690

Benzonitrile, 2-amino-5-chloro-

CAS: 5922-60-1

Formula: C₇H₅ClN₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 152.5810

Ref: IN-DA00IAIY

2-Amino-5-chlorobenzonitrile

CAS: 5922-60-1

2-Amino-5-chlorobenzonitrile

Formula: C₇H₅ClN₂

Purity: 98%

Color and Shape: pale yellow solid

Molecular weight: 152.58g/mol

Ref: 54-OR9761

2-Amino-5-chlorobenzonitrile

CAS: 5922-60-1

2-Amino-5-chlorobenzonitrile is a potent inhibitor of butyrylcholinesterase (BChE) and has been shown to inhibit the activity of this enzyme in cell lung cancer and muscle. 2-Amino-5-chlorobenzonitrile also inhibits the activity of other enzymes, such as acetylcholinesterase (AChE) and phosphatidylcholine esterase (PCE), that are found in the membranes of cells. This inhibition leads to increased levels of acetylcholine in the synaptic cleft, which may lead to an increase in muscular contractions. 2-Amino-5-chlorobenzonitrile is also a product yield enhancer for chromene synthesis.

Formula: C₇H₅ClN₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 152.58 g/mol

Ref: 3D-FA34609

2-Amino-5-chlorobenzonitrile

CAS: 5922-60-1

Formula: C₇H₅ClN₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 152.58

Ref: 10-F024204

2-Amino-5-chlorobenzonitrile

Controlled Product

CAS: 5922-60-1

Applications 2-Amino-5-chlorobenzonitrile is a reactant that has been used in the synthesis of pyrazine semicarbazide derivatives with herbicidal activity.
References Ma, Q., et. al.: Youji Huaxue, 33, 1749 (2013)

Formula: C₇H₅ClN₂

Color and Shape: Neat

Molecular weight: 152.58

Ref: TR-A602870

2-Amino-5-chlorobenzonitrile

CAS: 5922-60-1

Formula: C₇H₅ClN₂

Molecular weight: 152.58

Ref: ST-EA-CP-D18022