CAS 59247-13-1: (ganglioside gt1B) from bovine brain
Description:Ganglioside GT1b is a complex glycosphingolipid predominantly found in the nervous tissue, particularly in the brain of mammals, including bovines. It is characterized by its structure, which consists of a ceramide backbone linked to a carbohydrate moiety that includes sialic acid residues. This ganglioside plays a crucial role in cell signaling, neuronal development, and the modulation of synaptic transmission. GT1b is known for its involvement in various biological processes, including neuroprotection and cell recognition. Its presence in the brain contributes to the formation of lipid rafts, which are essential for the proper functioning of membrane proteins. Additionally, gangliosides like GT1b are implicated in neurodegenerative diseases and are studied for their potential therapeutic applications. The CAS number 59247-13-1 specifically identifies this compound, facilitating its recognition in scientific literature and databases. Overall, ganglioside GT1b is significant in neuroscience and biochemistry due to its structural complexity and functional importance in cellular interactions within the nervous system.
Formula:C88H157N5O44
InChI:InChI=1/C88H157N5O44/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-56(107)92-37-51(45(101)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)124-80-66(113)65(112)70(54(42-98)127-80)129-82-69(116)77(136-87(84(120)121)35-46(102)57(89)72(132-87)61(108)49(105)38-94)71(55(43-99)128-82)130-79-60(93-44(3)100)75(63(110)52(40-96)125-79)131-81-68(115)76(64(111)53(41-97)126-81)135-86(83(118)119)34-47(103)59(91)74(134-86)67(114)78(117)137-88(85(122)123)36-48(104)58(90)73(133-88)62(109)50(106)39-95/h30,32,45-55,57-82,94-99,101-106,108-117H,4-29,31,33-43,89-91H2,1-3H3,(H,92,107)(H,93,100)(H,118,119)(H,120,121)(H,122,123)/b32-30+/t45?,46-,47-,48-,49?,50?,51?,52-,53-,54+,55-,57+,58+,59+,60-,61?,62?,63+,64+,65+,66+,67?,68-,69-,70+,71+,72+,73+,74+,75-,76+,77-,78?,79+,80+,81+,82+,86+,87+,88+/m0/s1
- Synonyms:
- Ganglioside, GT1
- GT(1)Ganglioside
- GT1b Ganglioside
- Ganglioside GT1b
- N-Acetylneuraminylgalactosyl-N-acetylgalactosaminyl -(N-acetylneuraminyl-N-acetylneuraminyl)galactosyl- glucosylceramide
- Polysialoganglioside
- Trisialoganglioside GT1b
- (2R,4S,5R,6R)-2-[(2R,3S,4S,5R,6S)-5-[(2R,3S,4S,5S,6S)-3-acetamido-4-[(2S,3S,4R,5R,6S)-4-[(2R,4S,5R,6R)-5-amino-6-[2-[(2R,4S,5R,6R)-5-amino-2-carboxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-yl]oxy-1,2-dihydroxy-ethyl]-2-carboxy-4-hydroxy-tetrahydropyran-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(E)-2-hydroxy-1-[(octadecanoylamino)methyl]heptadec-3-enoxy]tetrahydropyran-3-yl]oxy-3-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxy-5-amino-4-hydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid
