CAS 5925-93-9

Benzonitrile, 2-amino-5-methyl-

Description:

Benzonitrile, 2-amino-5-methyl- is an organic compound characterized by the presence of both an amino group and a nitrile group attached to a benzene ring. Its molecular structure features a methyl group at the 5-position and an amino group at the 2-position relative to the nitrile. This compound is typically a colorless to pale yellow liquid with a distinctive aromatic odor. It is soluble in organic solvents and exhibits moderate solubility in water due to the polar nature of the amino and nitrile functional groups. The presence of the amino group can impart basic properties, allowing it to participate in various chemical reactions, such as nucleophilic substitutions. Benzonitrile derivatives are often used in the synthesis of pharmaceuticals, agrochemicals, and as intermediates in organic synthesis. Safety data indicates that it should be handled with care, as it may pose health risks upon exposure. Overall, 2-amino-5-methyl-benzonitrile is a versatile compound with applications in both research and industry.

Formula: C₈H₈N₂

InChI: InChI=1/C8H8N2/c1-6-2-3-8(10)7(4-6)5-9/h2-4H,10H2,1H3

SMILES: Cc1ccc(c(c1)C#N)N

Synonyms:

• 2-Amino-5-methylbenzonitril
• 2-Amino-5-methylbenzonitrile
• benzonitrile, 2-amino-5-methyl-

2-Amino-5-methylbenzonitrile

CAS: 5925-93-9

Formula: C₈H₈N₂

Purity: >97.0%(GC)

Color and Shape: White to Brown powder to crystal

Molecular weight: 132.17

Ref: 3B-A2843

2-Amino-5-methylbenzonitrile

CAS: 5925-93-9

2-Amino-5-methylbenzonitrile

Purity: 98%

Molecular weight: 132.16g/mol

Ref: 54-OR345378

2-Amino-5-methylbenzonitrile

CAS: 5925-93-9

2-Amino-5-methylbenzonitrile (2AMB) is a molecule that has two nitrile groups. It has been shown to be effective in the treatment of cancer cells, and it also inhibits thymidylate synthase (TS), an enzyme involved in DNA synthesis. The crystallographic structure of this compound has been determined by x-ray diffraction studies, and 2AMB was synthesized and assayed for its anticancer activity on human lung cancer cells in culture. 2AMB is an intercalator that binds to DNA by inserting itself between base pairs, which then blocks the progression of DNA synthesis during replication. This type of inhibition causes cell death because the cell cannot divide or make new proteins. Naphthalene and pyrrole are two chemicals found in 2AMB that have been shown to have antibacterial properties.

Formula: C₈H₈N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 132.16 g/mol

Ref: 3D-FA33035

2-Amino-5-methylbenzonitrile

CAS: 5925-93-9

Formula: C₈H₈N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 132.166

Ref: 10-F208806