CAS 592542-60-4

Rigosertib sodium

CAS: 592542-60-4

Rigosertib sodium

Purity: ≥98%

Molecular weight: 473.47g/mol

Ref: 54-BUP16257

Rigosertib sodium

CAS: 592542-60-4

Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.

Formula: C₂₁H₂₄NNaO₈S

Purity: 98% - 99.37%

Color and Shape: Solid

Molecular weight: 473.47

Ref: TM-T5818

Rigosertib sodium

CAS: 592542-60-4

Rigosertib sodium is an experimental chemotherapeutic agent that is a derivative of benzyl styryl sulfone. It is synthesized chemically and functions primarily by inhibiting key signaling pathways involved in cancer cell proliferation. Specifically, Rigosertib targets the RAS signaling pathway along with the phosphatidylinositol-3-kinase/AKT and polo-like kinase 1 (Plk1) pathways, impeding the progression of the cell cycle and inducing apoptosis in malignant cells.

Formula: C₂₁H₂₄NNaO₈S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 473.47 g/mol

Ref: 3D-BR175409