CAS 59264-04-9
:Rifamycin,1,4-dideoxy-1,4-dihydro-30-hydroxy-1,4-dioxo-
Description:
Rifamycin, 1,4-dideoxy-1,4-dihydro-30-hydroxy-1,4-dioxo- (CAS 59264-04-9) is a member of the rifamycin class of antibiotics, which are derived from the bacterium Amycolatopsis rifamycinica. This compound exhibits potent antibacterial activity, particularly against Mycobacterium tuberculosis, the causative agent of tuberculosis. Its structure features a complex bicyclic system with multiple functional groups, including hydroxyl and keto groups, which contribute to its biological activity. Rifamycins work by inhibiting bacterial RNA polymerase, thereby preventing RNA synthesis and ultimately leading to bacterial cell death. The compound is typically administered in combination with other antitubercular agents to enhance efficacy and reduce the risk of resistance development. Due to its specific action against mycobacterial infections, it is an essential drug in the treatment of tuberculosis and other mycobacterial diseases. However, its use may be limited by potential side effects and drug interactions, necessitating careful monitoring during therapy.
Formula:C37H45NO13
Synonyms:- 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan,rifamycin deriv.
- Rifamycin R
- Rifamycin, 1,4-dideoxy-1,4-dihydro-30-hydroxy-1,4-dioxo-
- 1,4-Dideoxy-30-hydroxy-1,4-dioxorifamycin
- Rifamycin Impurity 7
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