CAS 5927-18-4

Trimethyl phosphonoacetate

Description:

Trimethyl phosphonoacetate is an organophosphorus compound characterized by its phosphonate functional group. It typically appears as a colorless to pale yellow liquid with a fruity odor. This compound is known for its role as a versatile reagent in organic synthesis, particularly in the formation of phosphonate esters and as a precursor in the synthesis of various biologically active molecules. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water. Trimethyl phosphonoacetate is also recognized for its ability to act as a phosphonate source in reactions involving nucleophilic substitution. Safety considerations include handling it with care, as it may be harmful if ingested or inhaled, and it can cause skin and eye irritation. Proper storage in a cool, dry place away from incompatible materials is essential to maintain its stability and efficacy in chemical applications.

Formula: C₅H₁₁O₅P

InChI: InChI=1S/C5H11O5P/c1-8-5(6)4-11(7,9-2)10-3/h4H2,1-3H3

InChI key: InChIKey=SIGOIUCRXKUEIG-UHFFFAOYSA-N

SMILES: P(CC(OC)=O)(OC)(OC)=O

Synonyms:

• (Carboxymethyl)phosphonic acid trimethyl ester
• (Dimethoxyphosphinyl)acetic acid methyl ester
• Acetic acid, 2-(dimethoxyphosphinyl)-, methyl ester
• Acetic acid, phosphono-, trimethyl ester
• Carbomethoxymethanephosphonic acid dimethyl ester
• Dimethyl (carbomethoxymethyl)phosphonate
• Dimethyl (methoxycarbonyl)methylphosphonate
• Dimethyl (methoxycarbonylmethyl)phosphonate
• Dimethyl carbomethoxymethylphosphonate
• Dimethyl methoxycarbonylmethanephosphonate
• Fosfonoacetato De Trimetilo
• Methyl (dimethoxyphosphinyl)acetate
• Methyl 2-(dimethoxyphosphinyl)acetate
• Methyl 2-(dimethoxyphosphoryl)acetate
• Methyl 2-(dimethylphosphono)acetate
• Methyl dimethylphosphonoacetate
• Nsc 84262
• Phosphonoacetate de trimethyle
• Phosphonoacetic acid trimethyl ester
• Trimethyl Phosphonoacetate
• Trimethylphosphonoacetat
• [(Methoxycarbonyl)methyl]dimethylphosphonate
• Trimethyl phosphoroacetate
• methyl (dimethoxyphosphoryl)acetate
• Acetic acid, (dimethoxyphosphinyl)-, methyl ester

Trimethyl Phosphonoacetate

CAS: 5927-18-4

Formula: C₅H₁₁O₅P

Purity: >96.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 182.11

Ref: 3B-P1265

Trimethyl phosphonoacetate, 98%

CAS: 5927-18-4

Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyc

Formula: C₅H₁₁O₅P

Purity: 98%

Color and Shape: Clear, colourless, liquid

Molecular weight: 182.11

Ref: 02-A13301

Trimethyl Phosphonoacetate

CAS: 5927-18-4

Formula: C₅H₁₁O₅P

Purity: 99%

Color and Shape: Liquid

Molecular weight: 182.1116

Ref: IN-DA0035R9

Trimethyl phosphonoacetate

CAS: 5927-18-4

Trimethyl phosphonoacetate

Formula: C₅H₁₁O₅P

Purity: >98%

Color and Shape: Clear Liquid-Clear

Molecular weight: 182.1116

Ref: 54-OR52351

Methyl 2-(dimethoxyphosphoryl)acetate

CAS: 5927-18-4

Formula: C₅H₁₁O₅P

Purity: 99.00%

Color and Shape: Liquid

Molecular weight: 182.112

Ref: 10-F215697

Trimethyl phosphonoacetate

CAS: 5927-18-4

Trimethyl phosphonoacetate is an organic compound that is used as a reagent in the synthesis of other compounds. It can be prepared by a variety of methods including the reaction of trifluoroacetic acid with sodium carbonate and ammonia, or by the reaction of methyl chloride with trimethyl phosphite. Trimethyl phosphonoacetate is a precursor to many pharmaceuticals, including adenosine receptor antagonists and some anti-cancer drugs. Trimethyl phosphonoacetate has been shown to have beneficial effects on metabolic disorders such as chronic bronchitis and congestive heart failure.

Formula: C₅H₁₁O₅P

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 182.11 g/mol

Ref: 3D-FT139078

Trimethyl Phosphonoacetate

Controlled Product

CAS: 5927-18-4

Formula: C₅H₁₁O₅P

Color and Shape: Neat

Molecular weight: 182.11

Ref: TR-T798125

Trimethyl phosphonoacetate

CAS: 5927-18-4

Methyl 2-(dimethoxyphosphoryl)acetate

Formula: C₅H₁₁O₅P

Purity: 98%

Molecular weight: 182.11

Ref: IN-DG155444