CAS 59277-89-3

Acyclovir

Description:

Acyclovir is an antiviral medication primarily used to treat infections caused by certain types of viruses, particularly herpes simplex virus (HSV) and varicella-zoster virus (VZV). Its chemical formula is C8H10N5O3, and it is classified as a nucleoside analog. Acyclovir works by inhibiting viral DNA synthesis, thereby preventing the replication of the virus. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various formulations, including oral tablets, topical creams, and intravenous solutions. Acyclovir has a relatively low toxicity profile, but side effects can include nausea, diarrhea, and, in rare cases, renal toxicity, particularly with rapid intravenous administration. It is important to note that while acyclovir can effectively manage symptoms and reduce the duration of outbreaks, it does not cure herpes infections. The drug is often prescribed for both initial and recurrent episodes of herpes infections, as well as for prophylactic use in immunocompromised patients.

Formula: C₈H₁₁N₅O₃

InChI: InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)

InChI key: InChIKey=MKUXAQIIEYXACX-UHFFFAOYSA-N

SMILES: C(OCCO)N1C2=C(N=C1)C(=O)N=C(N)N2

Synonyms:

• 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
• 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one
• 2-Amino-9-(2-hydroxy-ethoxymethyl)-1,9-dihydro-purin-6-one
• 2-Amino-9-(2-hydroxy-ethoxymethyl)-3,9-dihydro-purin-6-one
• 2-Amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
• 2-Amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one
• 2-Amino-9-[(2-hydroxyethoxy)methyl]-9H-purin-6-ol
• 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-
• 9-(2-Hydroxyethoxymethyl)guanine
• 9-[(2-Hydroxyethoxy)methyl]guanine
• ACV
• Acicloftal
• Aciclovir
• Acivir
• Acyclo V
• Acyclovir
• Acyclovir (Patented-No Supply)
• Avirase
• Axiluowei
• BioVir I
• BioVir II
• Bw 248U
• Cargosil
• Gerpevir
• Herpevir
• Lovir
• N(9)-Oxyethoxymethylguanine (Acyclovir)
• Novirus
• Nsc 645011
• Poviral
• Rouz-Aciclovir
• Vicclox
• Vipral
• Virax
• Virless
• Virorax
• Virovir
• Wellcome 248U
• Zirax
• Zovirax
• Zyclir

Acyclovir

CAS: 59277-89-3

Formula: C₈H₁₁N₅O₃

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 225.21

Ref: 3B-A1915

Acycloguanosine, 98%

CAS: 59277-89-3

Inhibits cytomegalovirus replication; induces apoptosis

Formula: C₈H₁₁N₅O₃

Purity: 98%

Molecular weight: 225.2

Ref: 02-J64144

Aciclovir 1.0 mg/ml in Dimethyl Sulfoxide

CAS: 59277-89-3

Color and Shape: Single Solution

Ref: 61-AMP0061.00-29

Aciclovir

CAS: 59277-89-3

Color and Shape: Neat

Ref: 61-FOR0061.00

Aciclovir

CAS: 59277-89-3

Aciclovir

Formula: C₈H₁₁N₅O₃

Purity: 94.2%

Color and Shape: Off White Solid

Molecular weight: 225.08619

Ref: 47-438

ACICLOVIR CRS

CAS: 59277-89-3

ACICLOVIR CRS

Formula: C₈H₁₁N₅O₃

Molecular weight: 225.2046

Ref: 41-A0220000

ACICLOVIR FOR IMPURITY G IDENTIFICATION CRS

CAS: 59277-89-3

ACICLOVIR FOR IMPURITY G IDENTIFICATION CRS

Ref: 41-Y0002244

Acyclovir

CAS: 59277-89-3

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₈H₁₁N₅O₃

Color and Shape: White Powder

Molecular weight: 225.2

Ref: 45-1012065

2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-1H-purin-6-one

CAS: 59277-89-3

Formula: C₈H₁₁N₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 225.2046

Ref: IN-DA0034F0

Acyclovir

CAS: 59277-89-3

Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2,

Formula: C₈H₁₁N₅O₃

Purity: 99.77% - >99.99%

Color and Shape: Crystals From Methanol Solid

Molecular weight: 225.2

Ref: TM-T1454

Acyclovir

CAS: 59277-89-3

Formula: C₈H₁₁N₅O₃

Color and Shape: White To Off-White Solid

Molecular weight: 225.21

Ref: 4Z-A-0421

Acyclovir

CAS: 59277-89-3

Acyclovir

Formula: C₈H₁₁N₅O₃

Purity: By hplc: 98.5% (Typical Value in Batch COA)

Color and Shape: white crystalline powder

Molecular weight: 225.20g/mol

Ref: 54-BIA1250

Acyclovir

CAS: 59277-89-3

Formula: C₈H₁₁N₅O₃

Purity: 99.0 - 101.0 % (dried basis)

Color and Shape: White crystalline powder

Molecular weight: 225.20

Ref: 7W-GA7641

Acyclovir

CAS: 59277-89-3

Acyclovir

Purity: ≥98%

Molecular weight: 225.2g/mol

Ref: 54-BUP17021

Acyclovir, USP grade

CAS: 59277-89-3

Formula: C₈H₁₁N₅O₃

Purity: 98.0 - 101.0 %

Color and Shape: White to pale yellow crystalline powder

Molecular weight: 225.20

Ref: 7W-GA2411

Acyclovir

CAS: 59277-89-3

Acyclovir

Purity: 98%

Molecular weight: 225.20g/mol

Ref: 54-OR9240T

Aciclovir

Controlled Product

CAS: 59277-89-3

Formula: C₈H₁₁N₅O₃

Color and Shape: Neat

Molecular weight: 225.20

Ref: 86-MM0061.00

Acyclovir

CAS: 59277-89-3

Formula: C₈H₁₁N₅O₃

Color and Shape: Neat

Molecular weight: 225.20

Ref: 04-C10045600

2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one

CAS: 59277-89-3

Formula: C₈H₁₁N₅O₃

Purity: 95.0%

Color and Shape: Solid, White powder

Molecular weight: 225.208

Ref: 10-F076300

Aciclovir RS

CAS: 59277-89-3

Color and Shape: White To Pale Yellow-White Solid Crystalline Powder

Ref: 2K-1001500021

Valaciclovir EP Impurity B

CAS: 59277-89-3

Formula: C₈H₁₁N₅O₃

Molecular weight: 225.21

Ref: ST-EA-CP-V4002

Acyclovir

CAS: 59277-89-3

Formula: C₈H₁₁N₅O₃

Ref: TR-TRC-A192400

Acyclovir

CAS: 59277-89-3

Impurity Valaciclovir EP Impurity B
Applications Acyclovir (Valaciclovir EP Impurity B) is an orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral.
References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979), Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988), Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992)

Formula: C₈H₁₁N₅O₃

Color and Shape: Neat

Molecular weight: 225.2

Ref: TR-A192400

Acyclovir

CAS: 59277-89-3

Acyclovir is an antiviral drug that inhibits the replication of herpes viruses by selectively inhibiting viral DNA polymerase. The drug is active against a broad range of herpes viruses, including both types of herpes simplex virus (HSV-1 and HSV-2) and varicella zoster virus. Acyclovir has also been shown to be effective against aciclovir-resistant mutants. This drug can be used as a prophylaxis or in combination with other antiviral agents for the treatment of active infections. Acyclovir can cause headaches, nausea, vomiting, and diarrhea when taken orally. It should not be taken with certain medicines such as aminoglycosides or high doses of aspirin because this may increase the risk for kidney problems.

Formula: C₈H₁₁N₅O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 225.2 g/mol

Ref: 3D-IA58279