CAS 59277-89-3

Acyclovir

Description:

Acyclovir is an antiviral medication primarily used to treat infections caused by certain types of viruses, particularly herpes simplex virus (HSV) and varicella-zoster virus (VZV). Its chemical formula is C8H10N5O3, and it is classified as a nucleoside analog. Acyclovir works by inhibiting viral DNA synthesis, thereby preventing the replication of the virus. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various formulations, including oral tablets, topical creams, and intravenous solutions. Acyclovir has a relatively low toxicity profile, but side effects can include nausea, diarrhea, and, in rare cases, renal toxicity, particularly with rapid intravenous administration. It is important to note that while acyclovir can effectively manage symptoms and reduce the duration of outbreaks, it does not cure herpes infections. The drug is often prescribed for both initial and recurrent episodes of herpes infections, as well as for prophylactic use in immunocompromised patients.

Formula: C₈H₁₁N₅O₃

InChI: InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)

InChI key: InChIKey=MKUXAQIIEYXACX-UHFFFAOYSA-N

SMILES: C(OCCO)N1C2=C(N=C1)C(=O)N=C(N)N2

Synonyms:

• 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
• 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one
• 2-Amino-9-(2-hydroxy-ethoxymethyl)-1,9-dihydro-purin-6-one
• 2-Amino-9-(2-hydroxy-ethoxymethyl)-3,9-dihydro-purin-6-one
• 2-Amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
• 2-Amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one
• 2-Amino-9-[(2-hydroxyethoxy)methyl]-9H-purin-6-ol
• 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-
• 9-(2-Hydroxyethoxymethyl)guanine
• 9-[(2-Hydroxyethoxy)methyl]guanine
• ACV
• Acicloftal
• Aciclovir
• Acivir
• Acyclo V
• Acyclovir
• Acyclovir (Patented-No Supply)
• Avirase
• Axiluowei
• BioVir I
• BioVir II
• Bw 248U
• Cargosil
• Gerpevir
• Herpevir
• Lovir
• N(9)-Oxyethoxymethylguanine (Acyclovir)
• Novirus
• Nsc 645011
• Poviral
• Rouz-Aciclovir
• Vicclox
• Vipral
• Virax
• Virless
• Virorax
• Virovir
• Wellcome 248U
• Zirax
• Zovirax
• Zyclir

Aciclovir RS

CAS: 59277-89-3

Color and Shape: White To Pale Yellow-White Solid Crystalline Powder

Ref: 2K-1001500021

Acyclovir

CAS: 59277-89-3

Impurity Valaciclovir EP Impurity B
Applications Acyclovir (Valaciclovir EP Impurity B) is an orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral.
References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979), Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988), Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992)

Formula: C₈H₁₁N₅O₃

Color and Shape: Neat

Molecular weight: 225.20

Ref: TR-A192400

Valaciclovir EP Impurity B

CAS: 59277-89-3

Formula: C₈H₁₁N₅O₃

Molecular weight: 225.21

Ref: ST-EA-CP-V4002

Acyclovir

CAS: 59277-89-3

Acyclovir is an antiviral drug that inhibits the replication of herpes viruses by selectively inhibiting viral DNA polymerase. The drug is active against a broad range of herpes viruses, including both types of herpes simplex virus (HSV-1 and HSV-2) and varicella zoster virus. Acyclovir has also been shown to be effective against aciclovir-resistant mutants. This drug can be used as a prophylaxis or in combination with other antiviral agents for the treatment of active infections. Acyclovir can cause headaches, nausea, vomiting, and diarrhea when taken orally. It should not be taken with certain medicines such as aminoglycosides or high doses of aspirin because this may increase the risk for kidney problems.

Formula: C₈H₁₁N₅O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 225.2 g/mol

Ref: 3D-IA58279