CAS 59382-59-1

methyl 2-methyl-3-nitrobenzoate

Description:

Methyl 2-methyl-3-nitrobenzoate, with the CAS number 59382-59-1, is an organic compound belonging to the class of benzoates. It features a methyl ester functional group, which is derived from benzoic acid, and contains both a nitro group and a methyl substituent on the aromatic ring. This compound typically appears as a pale yellow to light brown liquid or solid, depending on its purity and form. It is characterized by its aromatic odor and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water. Methyl 2-methyl-3-nitrobenzoate is often used in organic synthesis and may serve as an intermediate in the production of various pharmaceuticals and agrochemicals. Its nitro group contributes to its reactivity, making it a useful building block in the synthesis of more complex molecules. Safety precautions should be taken when handling this compound, as nitro compounds can be hazardous and may pose environmental risks.

Formula: C₉H₉NO₄

InChI: InChI=1/C9H9NO4/c1-6-7(9(11)14-2)4-3-5-8(6)10(12)13/h3-5H,1-2H3

SMILES: Cc1c(cccc1N(=O)=O)C(=O)OC

Synonyms:

• 2-Methyl-3-nitrobenzoic acid methyl ester
• Methyl 2-Methyl-3-Nitrobenzenecarboxylate
• Methyl 3-Nitro-2-Methyl benzoate
• 2-Methyl-3-Nitromethyl Benzoate
• 2-Methyl-3-methyl nitrobenzene
• Methyl-2-Methyl-3-Nitrobenzoate

Methyl 2-Methyl-3-nitrobenzoate

CAS: 59382-59-1

Formula: C₉H₉NO₄

Purity: >98.0%(GC)

Color and Shape: White to Brown powder to crystal

Molecular weight: 195.17

Ref: 3B-M2144

Methyl 2-methyl-3-nitrobenzoate, 97%

CAS: 59382-59-1

Methyl 2-methyl-3-nitrobenzoate may be used in the synthesis of methyl indole-4-carboxylate, 5-aminoisoquinolin-1(2H)-one, 5-nitroisocoumarin and [2-(4-fluorophenyl)-1H-indol-4-yl]-1-pyrrolidinylmethanone. It may also be used in the preparation of substituted nitrostyrene benzoic acids, via reaction

Formula: C₉H₉NO₄

Purity: 97%

Molecular weight: 195.17

Ref: 02-H60242

Methyl 2-methyl-3-nitrobenzoate

CAS: 59382-59-1

Formula: C₉H₉NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 195.1721

Ref: IN-DA003ROO

Lenalidomide Impurity 23

CAS: 59382-59-1

Formula: C₉H₉NO₄

Color and Shape: Off-White Solid

Molecular weight: 195.17

Ref: 4Z-L-2629

Methyl 2-Methyl-3-nitrobenzoate

Controlled Product

CAS: 59382-59-1

Formula: C₉H₉NO₄

Color and Shape: Off White Solid

Molecular weight: 195.17

Ref: 86-MM3641.01

Methyl 2-methyl-3-nitrobenzoate

CAS: 59382-59-1

Methyl 2-methyl-3-nitrobenzoate

Purity: 98%

Molecular weight: 195.17g/mol

Ref: 54-OR25568

Methyl 2-Methyl-3-Nitrobenzoate

CAS: 59382-59-1

Formula: C₉H₉NO₄

Molecular weight: 195.17

Ref: ST-EA-CP-L27042

Methyl 2-methyl-3-nitrobenzoate

CAS: 59382-59-1

Methyl 2-methyl-3-nitrobenzoate is a synthetic drug that has potent antitumor activity and inhibits tumor growth in a variety of animal models. It acts by inhibiting protein synthesis and inducing apoptosis, as well as by inhibiting the production of TNF-α. Methyl 2-methyl-3-nitrobenzoate is an alkylating agent that reacts with DNA, RNA, and other cell components to form crosslinks between them. This prevents the cells from dividing or repairing themselves. The inhibition of protein synthesis may be due to methyl 2-methyl-3-nitrobenzoate's ability to react with amide groups on proteins.

Formula: C₉H₉NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 195.17 g/mol

Ref: 3D-FM15935

Methyl 2-methyl-3-nitrobenzoate

CAS: 59382-59-1

Formula: C₉H₉NO₄

Purity: 97%

Color and Shape: Solid, Pale yellow - Greyish yellow red crystal powder

Molecular weight: 195.174

Ref: 10-F078858

Methyl 2-Methyl-3-nitrobenzoate

Controlled Product

CAS: 59382-59-1

Applications Methyl 2-methyl-3-nitrobenzoate is used as a reagent to synthesize Lenalidomide (L328000). Lenalidomide is a compound that exhibits antimyeloma, anticancer and immunomodulatory activity and is used to treat patients with B-cell malignancies.
References Balaev, A., et al.: Pharm. Chem. J., 46, 676 (2013); Chanan-Khan, A. & Cheson, B.: J. Clin. Oncol., 26, 1544 (2008); Dredge, K., et al.: Microvasc. Res., 69, 56, 69 (2005); Palumbo, A., et al.: J. Clin. Oncol., 25, 4459 (2007)

Formula: C₉H₉NO₄

Color and Shape: Neat

Molecular weight: 195.17

Ref: TR-M320165