CAS: 5939-37-7 - 7-Hydroxymethotrexate

Formula: C₂₀H₂₂N₈O₆

InChI: InChI=1S/C20H22N8O6/c1-28(8-12-18(32)26-16-14(23-12)15(21)25-20(22)27-16)10-4-2-9(3-5-10)17(31)24-11(19(33)34)6-7-13(29)30/h2-5,11H,6-8H2,1H3,(H,24,31)(H,29,30)(H,33,34)(H5,21,22,25,26,27,32)/t11-/m0/s1

InChI key: InChIKey=HODZDDDNGRLGSI-NSHDSACASA-N

SMILES: O=C(O)CCC(NC(=O)C1=CC=C(C=C1)N(C)CC2=NC=3C(=NC(=NC3NC2=O)N)N)C(=O)O

Synonyms:

• 7-Hydroxymethotrexate
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2,4-diamino-1,7-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2,4-diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-
• Glutamic acid, N-[p-[[(2,4-diamino-7-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]-
• Glutamic acid, N-[p-[[(2,4-diamino-7-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-(+)-
• N-[(4-{[(2,4-diamino-7-oxo-7,8-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]-L-glutamic acid
• N-[(4-{[(2,4-diamino-7-oxo-7,8-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]glutamic acid
• N-[4-[[(2,4-Diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid
• NSC 380962
• N-[4-[[(2,4-Diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
• L-Glutamic acid, N-[4-[[(2,4-diamino-1,7-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-
• L-Glutamic acid, N-[4-[[(2,4-diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-
• Glutamic acid, N-[p-[[(2,4-diamino-7-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(+)-

7-HYDROXY METHOTREXATE

CAS: 5939-37-7

• Formula: C₂₀H₂₂N₈O₆
• Purity: 98%
• Molecular weight: 470.4387

7-Hydroxymethotrexate

CAS: 5939-37-7

7-Hydroxymethotrexate, major Methotrexate metabolite, inhibits dihydrofolate reductase and DNA synthesis by blocking folic acid conversion.

• Formula: C₂₀H₂₂N₈O₆
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 470.44

7-Hydroxy Methotrexate Trisodium Salt

CAS: 5939-37-7

• Formula: C₂₀H₁₉N₈O₆Na
• Color and Shape: Yellow Solid
• Molecular weight: 467.42 3*22.99

7-Hydroxy Methotrexate-d3 Ammonium Salt

CAS: 432545-62-5 5939-37-7

Applications 7-Hydroxy Methotrexate-d3 is a deuterated metabolite of Methotrexate, which is used as a antineoplastic …

• Formula: C₂₀H₂₂D₃N₉O₆
• Color and Shape: Neat
• Molecular weight: 490.49

7-Hydroxy Methotrexate Ammonium

CAS: 5939-37-7

Applications 7-Hydroxy Methotrexate Ammonium Salt is a metabolite of Methotrexate (M260675), which is used as …

• Formula: C₂₀H₂₂N₈O₆·NH₃
• Color and Shape: Neat
• Molecular weight: 487.47

7-Hydroxy methotrexate

CAS: 5939-37-7

Methotrexate is a chemotherapy drug that can be given intravenously or orally. It is used …

• Formula: C₂₀H₂₂N₈O₆
• Purity: Min. 95%
• Color and Shape: Yellow Solid
• Molecular weight: 470.44 g/mol