CAS 59403-54-2

1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine

Description:

1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine, commonly referred to as DPPC, is a phospholipid that plays a crucial role in cellular membranes, particularly in the formation of lipid bilayers. This compound features a glycerol backbone esterified with two fatty acids: palmitic acid (a saturated fatty acid) and docosahexaenoic acid (DHA, an omega-3 polyunsaturated fatty acid). The presence of these fatty acids imparts unique fluidity and flexibility properties to membranes, influencing their functionality and permeability. The phosphocholine head group contributes to the amphiphilic nature of the molecule, allowing it to interact with both hydrophilic and hydrophobic environments. DPPC is significant in various biological processes, including cell signaling and membrane dynamics, and is often studied in the context of lung surfactant, where it helps reduce surface tension in the alveoli. Additionally, it has applications in drug delivery systems and nanotechnology due to its biocompatibility and ability to form liposomes.

Formula: C₄₆H₈₀NO₈P

InChI: InChI=1S/C46H80NO8P/c1-6-8-10-12-14-16-18-20-21-22-23-24-25-27-29-31-33-35-37-39-46(49)55-44(43-54-56(50,51)53-41-40-47(3,4)5)42-52-45(48)38-36-34-32-30-28-26-19-17-15-13-11-9-7-2/h8,10,14,16,20-21,23-24,27,29,33,35,44H,6-7,9,11-13,15,17-19,22,25-26,28,30-32,34,36-43H2,1-5H3/b10-8-,16-14-,21-20-,24-23-,29-27-,35-33-/t44-/m1/s1

InChI key: InChIKey=IESVDEZGAHUQJU-ZLBXKVHBSA-N

SMILES: [C@H](OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCC)=O

Synonyms:

• 1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine
• 3,5,8-Trioxa-4-phosphatriaconta-12,15,18,21,24,27-hexaen-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, [R-(all-Z)]-
• 3,5,8-Trioxa-4-phosphatriaconta-12,15,18,21,24,27-hexaen-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (7R,12Z,15Z,18Z,21Z,24Z,27Z)-
• Palmitoyldocosahexaenoylphosphatidylcholine

Palmitoyldocosahexaenoyl phosphatidylcholine

CAS: 59403-54-2

Palmitoyldocosahexaenoyl phosphatidylcholine is a polyunsaturated fatty acid that mimics special cell membrane structural domain lipids.

Formula: C₄₆H₈₀NO₈P

Purity: 98%

Color and Shape: Solid

Molecular weight: 806.1

Ref: TM-T12357

1-Palmitoyl-2-Docosahexaenoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 59403-54-2

Formula: C46H80NO8P

Purity: >98%

Color and Shape: Solid

Molecular weight: 806.1

Ref: 48-37-1625

Palmitoyldocosahexaenoyl phosphatidylcholine

CAS: 59403-54-2

Palmitoyldocosahexaenoyl phosphatidylcholine (PC-S) is a fatty acid with six double bonds. It has been shown to induce osteogenic genes in human macrophages and can be used as a potential therapeutic agent for the treatment of bone diseases. PC-S also has anti-inflammatory properties, which is due to its ability to inhibit secretory phospholipase A2 (sPLA2). PC-S is structurally similar to the polyunsaturated fatty acid linoleic acid and has been found to have reactive properties. PC-S may be used as an adjuvant therapy for cancer and other diseases, such as Alzheimer's disease. Clinical studies are currently being conducted.

Formula: C₄₆H₈₀NO₈P

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 806.1 g/mol

Ref: 3D-FP26733