CAS 5945-86-8

Nimbin

Description:

Nimbin, with the CAS number 5945-86-8, is a naturally occurring alkaloid primarily found in the leaves of the plant *Nimba* (Azadirachta indica), commonly known as neem. This compound is known for its diverse biological activities, including antimicrobial, anti-inflammatory, and insecticidal properties, making it of interest in both pharmacological and agricultural applications. Nimbin exhibits a complex molecular structure, which contributes to its ability to interact with various biological targets. It is often studied for its potential therapeutic effects, particularly in traditional medicine, where neem has been used for centuries. The substance is typically characterized by its solubility in organic solvents and limited solubility in water, which influences its bioavailability and efficacy in different formulations. Additionally, nimbin's safety profile and environmental impact are subjects of ongoing research, particularly in the context of sustainable agriculture and natural pest control. Overall, nimbin represents a significant compound within the realm of natural products chemistry, with promising applications in health and agriculture.

Formula: C₃₀H₃₆O₉

InChI: InChI=1S/C30H36O9/c1-15-18(17-9-11-37-14-17)12-19-23(15)30(5)20(13-22(33)35-6)29(4)21(32)8-10-28(3,27(34)36-7)25(29)24(26(30)39-19)38-16(2)31/h8-11,14,18-20,24-26H,12-13H2,1-7H3/t18-,19-,20-,24-,25+,26-,28-,29+,30-/m1/s1

InChI key: InChIKey=NHOIBRJOQAYBJT-IMGVWCFESA-N

SMILES: C[C@@]12[C@@]([C@H](OC(C)=O)[C@@]3([C@@](C)([C@H]1CC(OC)=O)C(=O)C=C[C@]3(C(OC)=O)C)[H])(O[C@]4(C2=C(C)[C@@H](C4)C=5C=COC5)[H])[H]

Synonyms:

• (4a,5a,6a,7a,15b,17a)-6-(Acetyloxy)-7,15:21,23-diepoxy-4,8-dimethyl-1-oxo-18,24-dinor-11,12-secochola-2,13,20,22-tetraene-4,11-dicarboxylic Acid Dimethyl Ester
• 18,24-Dinor-11,12-secochola-2,13,20,22-tetraene-4,11-dicarboxylic acid, 6-(acetyloxy)-7,15:21,23-diepoxy-4,8-dimethyl-1-oxo-, dimethyl ester, (4α,5α,6α,7α,15β,17α)-
• 2H-Cyclopenta[b]naphtho[2,3-d]furan-10-acetic acid, 5-(acetyloxy)-2-(3-furanyl)-3,3a,4a,5,5a,6,9,9a,10,10a-decahydro-6-(methoxycarbonyl)-1,6,9a,10a-tetramethyl-9-oxo-, methyl ester, (2R,3aR,4aS,5R,5aR,6R,9aR,10S,10aR)-
• 2H-Cyclopenta[b]naphtho[2,3-d]furan-10-acetic acid, 5-(acetyloxy)-2-(3-furanyl)-3,3a,4a,5,5a,6,9,9a,10,10a-decahydro-6-(methoxycarbonyl)-1,6,9a,10a-tetramethyl-9-oxo-, methyl ester, [2R-(2α,3aα,4aβ,5α,5aα,6α,9aβ,10β,10aβ)]-
• 2H-Cyclopenta[b]naphtho[2,3-d]furan-10-acetic acid, 6α-carboxy-2α-(3-furyl)-3,3aα,4aβ,5,5aα,6,9,9a,10α,10a-decahydro-5α-hydroxy-1,6,9aβ,10aβ-tetramethyl-9-oxo-, dimethyl ester, acetate
• 2H-Cyclopenta[b]naphtho[2,3-d]furan-10-acetic acid, 6β-carboxy-2α-(3-furyl)-3,3aβ,4aβ,5,5aα,6,9,9a,10,10a-decahydro-5α-hydroxy-1,6,9aβ,10aβ-tetramethyl-9-oxo-, dimethyl ester, acetate
• 5945-86-8
• Methyl (2R,3aR,4aS,5R,5aR,6R,9aR,10S,10aR)-5-acetoxy-2-(3-furyl)-10-(2-methoxy-2-oxoethyl)-1,6,9a,10a-tetramethyl-9-oxo-3,3a,4a,5,5a,6,9,9a,10,10a-decahydro-2H-cyclopenta[b]naphtho[2,3-d]furan-6-carboxylate
• Nimbin

Nimbin

CAS: 5945-86-8

Formula: C₃₀H₃₆O₉

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 540.6014

Ref: IN-DA00EAAU

Nimbin

CAS: 5945-86-8

Nimbin: anti-pyretic, treats arthritis, hypoglycemia, ulcers; acts as antibiotic; inhibits steroid hydroxylase; toxic to Lepidoptera larvae and locust nymphs.

Formula: C₃₀H₃₆O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 540.6

Ref: TM-TN4659

Nimbin

CAS: 5945-86-8

Formula: C₃₀H₃₆O₉

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 540.609

Ref: BP-SBP02317

Nimbin

CAS: 5945-86-8

Applications A new limonoid from Arisaema decipiens, a traditional antitumor herb.
References Cohen, E., et al.: Life Sci., 58, 1075 (1996), Roy, A., et al.: Biol. Pharm. Bull., 29, 191 (2006),

Formula: C₃₀H₃₆O₉

Color and Shape: White To Beige

Molecular weight: 540.60

Ref: TR-N476280

Nimbin

CAS: 5945-86-8

Nimbin is a bioactive compound derived from the neem tree, Azadirachta indica, a member of the Meliaceae family. It is a natural triterpenoid, which acts as an active secondary metabolite. Nimbin is primarily obtained through the extraction and isolation from neem seed kernels or leaves, employing methods such as solvent extraction and chromatography.

Formula: C₃₀H₃₆O₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 540.6 g/mol

Ref: 3D-FN26221

Nimbin

CAS: 5945-86-8

Formula: C₃₀H₃₆O₉

Molecular weight: 540.61

Ref: 4Z-L-215003