CAS 59450-89-4

calcimycin A23187 hemicalcium salt

Description:

Calcimycin A23187 hemicalcium salt, with the CAS number 59450-89-4, is a calcium ionophore that facilitates the transport of calcium ions across biological membranes. This compound is known for its ability to selectively bind calcium ions, which can influence various cellular processes, including muscle contraction, neurotransmitter release, and signal transduction pathways. Calcimycin exhibits a lipophilic nature, allowing it to traverse lipid membranes easily. It is often utilized in research settings to study calcium signaling and its effects on cellular functions. Additionally, calcimycin has been investigated for its potential therapeutic applications, including its role in enhancing the efficacy of certain anticancer drugs by modulating calcium levels within cells. However, its use must be approached with caution due to potential cytotoxic effects at high concentrations. Overall, calcimycin A23187 hemicalcium salt serves as a valuable tool in biochemistry and pharmacology for understanding calcium's role in various physiological and pathological processes.

Formula: C₅₈H₇₂CaN₆O₁₂

Synonyms:

• calcium ionophore A23187 hemicalcium
• Calcium Ionophore A23187 hemicalcium salt powder
• 5-(methylamino)-2-[[(2S,3R,5R,6S,8R,9R)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylate
• CALCIUM IONOPHORE A23187 HEMICALCIUM SALT BIOCHEMIKA
• 5-(methylamino)-2-[[(2S,3R,5R,8R,9R)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylate
• A23187 HEMICALCIUM SALT
• CALCIMYCIN A23187 HEMICALCIUM SALT
• Antibiotic A-23187 hemicalcium salt
• CALCIUM IONOPHORE A23187 HEMICALCIUM SALT
• A23187 hemicalcium salt, Antibiotic A 23187 hemicalcium salt, Calcimycin hemicalcium salt, Calimycin hemicalcium salt

Calcimycin hemicalcium salt

CAS: 59450-89-4

Calcimycin (A-23187) is an antibiotic calcium ionophore that raises intracellular Ca2+ to induce cell death.

Formula: C₅₈H₇₂CaN₆O₁₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1085.322

Ref: TM-T10662

Calcium Ionophore A23187 hemicalcium salt

CAS: 59450-89-4

Formula: C₂₉H₃₆Ca₀·5N₃O₆

Molecular weight: 542.65

Ref: 7W-GL6748

Calcium Ionophore A23187 hemicalcium salt

CAS: 59450-89-4

Calcium ionophore A23187 is a drug that was developed as a treatment for bacterial disease. It has been used to treat coccidiosis in chickens and toxoplasmosis in pigs. The uptake of calcium ionophore A23187 is synchronous with the availability of free intracellular calcium ions, which is necessary for the development of the effect. The concentrations of the drug are dependent on the uptake rate and the concentration gradient between inside and outside the cell. Calcium ionophore A23187 can be used to control bleeding by inhibiting platelet aggregation and clot formation. It also may be used as an adjuvant in tissue engineering devices that require hemostasis, such as vascular grafts or synthetic blood vessels.

Formula: C₂₉H₃₆Ca₀·5N₃O₆

Purity: Min. 95%

Molecular weight: 542.65 g/mol

Ref: 3D-JCA45089