CAS 59467-68-4

Acetamide,N-[[7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methyl]-

Description:

Acetamide, N-[[7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methyl]- is a chemical compound characterized by its complex structure, which includes a benzodiazepine core. This compound features a chloro substituent and a fluorophenyl group, contributing to its unique pharmacological properties. It is classified as an amide due to the presence of the acetamide functional group, which is known for its ability to form hydrogen bonds, enhancing solubility in polar solvents. The presence of the benzodiazepine moiety suggests potential activity in the central nervous system, often associated with anxiolytic, sedative, or anticonvulsant effects. The specific arrangement of substituents influences its biological activity and interaction with various receptors. Additionally, the compound's molecular weight, melting point, and solubility characteristics would be relevant for its application in medicinal chemistry and pharmacology. Safety and handling precautions are essential, as with many compounds in this class, due to potential toxicity or side effects.

Formula: C₁₈H₁₇ClFN₃O

N-((7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide-13C2

Controlled Product

CAS: 59467-68-4

Applications N-((7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide-13C2 is an intermediate in the synthesis of Midazolam-13C2 the labeled analogue of Midazolam (M343000), an anesthetic; anticonvulsant; sedative; hypnotic.
References Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000)

Formula: C₂C₁₆H₁₇ClFN₃O

Color and Shape: Neat

Molecular weight: 347.784

Ref: TR-C366962

Midazolam Impurity 17

CAS: 59467-68-4

Formula: C₁₈H₁₇ClFN₃O

Molecular weight: 345.80

Ref: ST-EA-CP-M85035