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CAS 59467-70-8

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Midazolam

Description:
Midazolam is a short-acting benzodiazepine commonly used for its sedative, anxiolytic, and amnesic properties. It is characterized by its rapid onset of action, making it particularly useful in medical settings for procedures requiring sedation, such as endoscopies or surgeries. Midazolam is typically administered intravenously, intramuscularly, or orally, and it is known for its effectiveness in inducing sedation while allowing for quick recovery. The substance acts primarily by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased inhibitory neurotransmission in the central nervous system. Midazolam is also notable for its relatively short half-life, which allows for precise control over sedation levels. However, it can cause side effects such as respiratory depression, especially when used in combination with other central nervous system depressants. Due to its potential for dependence and abuse, midazolam is classified as a controlled substance in many jurisdictions. Its chemical structure includes a 1,2-benzodiazepine ring, contributing to its pharmacological effects.
Formula:C18H13ClFN3
InChI:InChI=1S/C18H13ClFN3/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13/h2-9H,10H2,1H3
InChI key:InChIKey=DDLIGBOFAVUZHB-UHFFFAOYSA-N
SMILES:CC=1N2C=3C(C(=NCC2=CN1)C4=C(F)C=CC=C4)=CC(Cl)=CC3
Synonyms:
  • 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
  • Adv 6209
  • Buccolam
  • Dazolam
  • Dormicum
  • Gobbizolam
  • Mezolam
  • Midacom
  • Midanium
  • Midazolam
  • See more synonyms
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Found 14 products.
  • Midazolam 1.0 mg/ml in Methanol

    Controlled Product
    CAS:
    Color and Shape:Single Solution

    Ref: 61-AMP1106.00-01

    1ml
    86.00€
  • Midazolam

    Controlled Product
    CAS:
    Color and Shape:Neat

    Ref: LP-MID-111-FB-10

    10mg
    174.00€
    50mg
    839.00€
    100mg
    1,629.00€
  • Midazolam, 1mg/ml in Methanol

    Controlled Product
    CAS:
    Color and Shape:Single Solution

    Ref: LP-MID-111-FB-1LM

    1ml
    48.00€
  • Midazolam 0.1 mg/ml in Methanol

    Controlled Product
    CAS:
    Color and Shape:Single Solution

    Ref: 61-AMP1106.00-02

    1ml
    72.00€
  • Midazolam

    Controlled Product
    CAS:
    Color and Shape:Neat

    Ref: 86-MM1106.00

    250mg
    1,609.00€
  • Midazolam

    Controlled Product
    CAS:
    Color and Shape:Neat

    Ref: 61-FOR1106.00

    10mg
    336.00€
  • Midazolam

    Controlled Product
    CAS:
    <p>Applications Anesthetic; anticonvulsant; sedative; hypnotic. Positive allosteric modulator of the GABAA receptor. Neuroprotective &amp; Neuroresearch products.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>
    Formula:C18H13ClFN3
    Color and Shape:White To Off-White
    Molecular weight:325.77

    Ref: TR-M343000

    1g
    2,264.00€
    100mg
    340.00€
    250mg
    733.00€
  • Midazolam

    Controlled Product
    CAS:
    <p>Midazolam is an imidazopyridine that is used as a sedative and hypnotic. It is chemically stable, which makes it suitable for use in injection solutions, nasal drugs, and tablets. Midazolam has been shown to have a rapid onset of action and short duration of effect, which are desirable qualities for a drug to be used as pre-operative medication or for sedation during diagnostic or therapeutic procedures. The kinetic energy of midazolam is dependent on the concentration–time curve in the central nervous system (CNS). This drug also interacts with other drugs such as triazolam, mianserin hydrochloride, and phenytoin, which increases the likelihood of adverse effects. Midazolam has also been shown to cause neuronal death by inhibiting the production of nitric oxide synthase.</p>
    Formula:C18H13ClFN3
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:325.77 g/mol

    Ref: 3D-FM25999

    10mg
    303.00€
    25mg
    343.00€
    50mg
    496.00€
    100mg
    679.00€
    300mg
    1,399.00€
  • MIDAZOLAM CRS - * PSY

    Controlled Product
    CAS:
    <p>MIDAZOLAM CRS - * PSY</p>
    Formula:C18H13ClFN3
    Color and Shape:Crystalline Powder. White. Light Yellow. Powder.
    Molecular weight:325.7673

    Ref: 41-M2200000

    50mg
    115.00€
  • MIDAZOLAM FOR SYSTEM SUITABILITY CRS - * PSY (MIDAZOLAM)

    Controlled Product
    CAS:
    <p>MIDAZOLAM FOR SYSTEM SUITABILITY CRS - * PSY (MIDAZOLAM)</p>
    Formula:C18H13ClFN3
    Color and Shape:Crystalline Powder. White. Light Yellow. Powder.
    Molecular weight:325.7673

    Ref: 41-Y0000599

    1mg
    115.00€
  • Midazolam

    Controlled Product
    CAS:
    Midazolam
    Formula:C18H13ClFN3
    Purity:99.9%
    Color and Shape:White To Off-White
    Molecular weight:325.0782

    Ref: 47-722

    100mg
    242.00€
  • Midazolam (1.0 mg/mL in methanol)

    Controlled Product
    CAS:
    Formula:C18H13ClFN3
    Color and Shape:Colourless
    Molecular weight:325.77

    Ref: TR-KIT0040

    10x1ml
    1,063.00€
  • Midazolam-13C2

    Controlled Product
    CAS:
    <p>Applications Midazolam-13C2 is the labeled analogue of Midazolam (M343000), an anesthetic; anticonvulsant; sedative; hypnotic.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>
    Formula:C2C16H13ClFN3
    Color and Shape:Neat
    Molecular weight:327.753

    Ref: TR-M343001

    1mg
    360.00€
    10mg
    2,489.00€
  • Midazolam CIV

    Controlled Product
    CAS:
    Alprazolam(inn), camazepam (inn), chlordiazepoxide (inn), clonazepam (inn), clorazepate & other heterocyclic compounds with nitro atom(s) only
    Formula:C18H13ClFN3
    Color and Shape:Yellow White Crystalline Powder
    Molecular weight:325.0782