CAS 59467-96-8: Midazolam hydrochloride

Description: Midazolam hydrochloride is a medication belonging to the benzodiazepine class, primarily used for its sedative, anxiolytic, and amnesic properties. It is commonly administered in medical settings for procedural sedation, induction of anesthesia, and as an adjunct in various therapeutic protocols. The substance appears as a white to off-white crystalline powder, which is soluble in water and alcohol, facilitating its use in injectable formulations. Midazolam acts on the central nervous system by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA), leading to increased sedation and reduced anxiety. Its pharmacokinetics are characterized by rapid onset and a relatively short duration of action, making it suitable for short procedures. The hydrochloride salt form enhances its stability and solubility. As with other benzodiazepines, midazolam carries a risk of dependence and withdrawal symptoms, necessitating careful monitoring during use. It is classified as a controlled substance in many jurisdictions due to its potential for abuse and misuse.

Formula: C₁₈H₁₃ClFN₃·ClH

InChI: InChI=1S/C18H13ClFN3.ClH/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13;/h2-9H,10H2,1H3;1H

InChI key: InChIKey=PLYSCVSCYOQVRP-UHFFFAOYSA-N

SMILES: Cl.FC=1C=CC=CC1C2=NCC3=CN=C(N3C=4C=CC(Cl)=CC24)C

Synonyms:

• 4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-, hydrochloride (1:1)
• 4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-, monohydrochloride
• 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine hydrochloride (1:1)
• Hypnovel
• Midazolam Hydrochloride
• Ro 21-3981/003
• Rocam
• Syrpalta
• Versed

Midazolam Hydrochloride

CAS: 59467-96-8

• Formula: C₁₈H₁₃ClFN₃·ClH
• Color and Shape: Neat
• Molecular weight: 362.23

Midazolam hydrochloride

CAS: 59467-96-8

Midazolam hydrochloride is a sedative and minor tranquilizer that has minimal toxicity. It is used …

• Formula: C₁₈H₁₃ClFN₃•HCl
• Molecular weight: 362.23 g/mol

Midazolam hydrochloride

CAS: 59467-96-8

Allosteric modulator of GABA(A) receptors

• Formula: C₁₈H₁₃ClFN₃•HCl
• Purity: Min. 95%
• Color and Shape: White Off-White Powder
• Molecular weight: 362.23 g/mol

Midazolam Hydrochloride CIV

CAS: 59467-96-8

Alprazolam(inn), camazepam (inn), chlordiazepoxide (inn), clonazepam (inn), clorazepate & other heterocyclic compounds with nitro atom(s) …

• Formula: C₁₈H₁₃ClFN₃·HCl
• Color and Shape: Light Yellow Powder
• Molecular weight: 361.05488