CAS 59481-77-5

Boc-Met-Enkephalin

Description:

Boc-Met-Enkephalin is a synthetic peptide that serves as a derivative of the natural opioid peptide Met-enkephalin, which is involved in pain modulation and various physiological processes. The "Boc" in its name refers to the tert-butyloxycarbonyl (Boc) protecting group, commonly used in peptide synthesis to protect the amino group of the amino acid during the coupling process. This compound typically consists of five amino acids, with methionine (Met) being the first in the sequence, followed by other residues that contribute to its biological activity. Boc-Met-Enkephalin is characterized by its ability to bind to opioid receptors, particularly the delta and mu receptors, which play a crucial role in analgesia and the modulation of mood. Its structure allows for increased stability and bioavailability compared to its unprotected counterpart. This peptide is often utilized in research to study opioid receptor interactions and the development of analgesic drugs. As with many peptides, it may exhibit specific solubility characteristics and stability profiles depending on the conditions of use.

Formula: C₃₂H₄₃N₅O₉S

Synonyms:

• Boc-Tyr-Gly-Gly-Phe-Met-OH
• N-ALPHA-T-BOC-[MET5]-ENKEPHALIN
• N-ALPHA-T-BOC-L-TYR-GLY-GLY-PHE-MET
• BOC-MET-ENKEPHALIN
• L-Methionine, N-[(1,1-dimethylethoxy)carbonyl]-L-tyrosylglycylglycyl-L-phenylalanyl-
• Boc-Met-Enkephalin Boc-Tyr-Gly-Gly-Phe-Met-OH
• BOC-TYR-GLY-GLY-PHE-MET
• N-[(1,1-Dimethylethoxy)carbonyl]-L-tyrosylglycylglycyl-L-phenylalanyl-L-methionine

Boc-Met-Enkephalin

CAS: 59481-77-5

Boc-Met-Enkephalin is a hexapeptide that is derived from the amino acid Met. It is related to the opioid peptide Met-enkephalin, which has been shown to be involved in pain modulation and emotional responses such as fear and pleasure. Boc-Met-Enkephalin was synthesized by coupling two different fragments through an amide bond. The sequential order of these fragments was determined by high-resolution NMR spectroscopy. The carbonyl groups on the peptides were identified by using heteronuclear 2D correlation experiments. This sequence of carbons was demonstrated with 13C and 15N spectroscopy, in which it was found that there are three molecules of methylene carbon per molecule of Boc-Met-Enkephalin.

Formula: C₃₂H₄₃N₅O₉S

Purity: Min. 95%

Molecular weight: 673.78 g/mol

Ref: 3D-FB111226