CAS 5949-16-6

Cinchonine sulfate

Description:

Cinchonine sulfate is a chemical compound derived from cinchonine, an alkaloid obtained from the bark of the cinchona tree. It is primarily recognized for its use in medicinal applications, particularly as an antimalarial agent and in the treatment of certain types of arrhythmias. The compound is typically encountered as a white to off-white crystalline powder, which is soluble in water and exhibits a slightly bitter taste. Cinchonine sulfate has a molecular formula that reflects its sulfate salt form, which enhances its solubility and bioavailability compared to its parent alkaloid. In addition to its pharmacological properties, cinchonine sulfate may also exhibit some degree of antimicrobial activity. However, its use is often limited by potential side effects, including gastrointestinal disturbances and allergic reactions. As with many alkaloids, the safety and efficacy of cinchonine sulfate depend on proper dosage and administration, necessitating careful consideration in therapeutic contexts.

Formula: C₁₉H₂₂N₂OH₂O₄S

InChI: InChI=1S/C19H22N2O.H2O4S/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17;1-5(2,3)4/h2-7,9,13-14,18-19,22H,1,8,10-12H2;(H2,1,2,3,4)/t13-,14-,18+,19-;/m0./s1

InChI key: InChIKey=KFHZMXDENPHHOU-BKUXTCEESA-N

SMILES: S(=O)(=O)(O)O.[C@@H](O)([C@@]1([N@@]2C[C@H](C=C)[C@](C1)(CC2)[H])[H])C=3C4=C(N=CC3)C=CC=C4

Synonyms:

• (5E)-1-(4-chlorophenyl)-5-(3,5-dichloro-4-methoxybenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
• Bis(9-Hydroxycinchonan-1-Ium) Sulfate
• Cinchonan-9-ol, (9S)-, sulfate (2:1)
• Cinchonan-9-ol, (9S)-, sulfate (2:1) (salt)
• Cinchonine Sulphate
• Cinchonine sulfate
• Cinchonine, sulfate (2:1) (salt)
• Cinchoninesulfate

Cinchonine Sulfate Dihydrate

CAS: 5949-16-6

Formula: C₃₈H₄₄N₄O₂·H₂SO₄·2H₂O

Purity: >98.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 722.90

Ref: 3B-C0791

Cinchonine sulfate

CAS: 5949-16-6

Formula: C₃₈H₄₆N₄O₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 686.8600

Ref: IN-DA003OWQ

Cinchonine Sulfate Dihydrate

CAS: 5949-16-6

Cinchonine Sulfate Dihydrate

Purity: 98%

Ref: 54-OR1029182

Cinchonine sulfate

CAS: 5949-16-6

Formula: C₁₉H₂₄N₂O₅S

Molecular weight: 392.47

Ref: 7W-GP8997

Cinchonine Hemisulfate Salt

Controlled Product

CAS: 5949-16-6

Applications Cinchonine Hemisulfate Salt causes a complete cardioinhibitory effect of vagus stimulation in dogs; Cinchona alkaloids.
References Hiatt, E. P., et al.: J. Pharmacol., 85, 55-60 (1945)

Formula: (C₁₉H₂₂N₂O)·(H₂O₄S)

Color and Shape: Neat

Molecular weight: 2(294.39) + (98.08)

Ref: TR-C441943