CAS 59496-25-2

1H-Indole-3-carbonyl chloride

CAS: 59496-25-2

Formula: C₉H₆ClNO

Molecular weight: 179.6030

Ref: IN-DA00E9E7

1H-Indole-3-carbonyl chloride

CAS: 59496-25-2

1H-Indole-3-carbonyl chloride

Formula: C₉H₆ClNO

Purity: 90%

Color and Shape: brown powder

Molecular weight: 179.60g/mol

Ref: 54-OR111176

1H-Indole-3-carbonyl chloride

CAS: 59496-25-2

Formula: C₉H₆ClNO

Purity: 97.0%

Molecular weight: 179.6

Ref: 10-F402864

1H-Indole-3-carbonyl chloride

CAS: 59496-25-2

1H-Indole-3-carbonyl chloride is a chemical compound that has been shown to have anticancer activity. It binds selectively to the 5-HT4 receptor, inhibiting the growth of colorectal adenocarcinoma cells in cell culture. The binding of 1H-indole-3-carbonyl chloride to the 5HT4 receptor leads to an increase in intracellular calcium, which inhibits proliferation and induces apoptosis. 1H-Indole-3-carbonyl chloride also inhibits fatty acid synthesis in bacteria such as Escherichia coli and Saccharomyces cerevisiae. This compound can be synthesized from 1H-indole and chloroformate using a method called Grignard reaction.

Formula: C₉H₆NOCl

Purity: Min. 95%

Molecular weight: 179.6 g/mol

Ref: 3D-JCA49625